Q8K561 · OTOAN_MOUSE

  • Protein
    Otoancorin
  • Gene
    Otoa
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

May act as an adhesion molecule.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcell surface
Cellular Componentextracellular region
Cellular Componentside of membrane
Biological Processcell-matrix adhesion
Biological Processmulticellular organism growth
Biological Processsensory perception of sound
Biological Processtransmission of nerve impulse

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Otoancorin

Gene names

    • Name
      Otoa

Organism names

  • Taxonomic identifier
  • Strain
    • BALB/cJ
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q8K561

Proteomes

Organism-specific databases

Subcellular Location

Apical cell membrane
; Lipid-anchor, GPI-anchor
Note: At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes.

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation, lipidation, propeptide.

TypeIDPosition(s)Description
Signal1-23
ChainPRO_000002197324-1113Otoancorin
Glycosylation156N-linked (GlcNAc...) asparagine
Glycosylation211N-linked (GlcNAc...) asparagine
Glycosylation244N-linked (GlcNAc...) asparagine
Glycosylation289N-linked (GlcNAc...) asparagine
Glycosylation321N-linked (GlcNAc...) asparagine
Glycosylation380N-linked (GlcNAc...) asparagine
Glycosylation384N-linked (GlcNAc...) asparagine
Glycosylation530N-linked (GlcNAc...) asparagine
Glycosylation594N-linked (GlcNAc...) asparagine
Glycosylation740N-linked (GlcNAc...) asparagine
Glycosylation798N-linked (GlcNAc...) asparagine
Lipidation1113GPI-anchor amidated glycine
PropeptidePRO_00000219741114-1137Removed in mature form

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in the inner ear and vestibule.

Developmental stage

Expressed in cochlea on the upper surface of the spiral limbus at 16.5 dpc onwards.

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1095-1119Disordered

Sequence similarities

Belongs to the stereocilin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    1,137
  • Mass (Da)
    126,430
  • Last updated
    2002-10-01 v1
  • Checksum
    4AD20F631FE8A8A2
MSQGPRTCSLLLVLLLSHGGAYQREPSPRQDLHPLLQKMAEEIIEGSYLNALLDLTLFERSHVWTADLSHRVLAYLNSKNVAFTIPSLQAVMEAHLEQYLYQPQKLLEDLRATDNQQFHTAMKCLLEDKWGHLDLEDVVINLGDIRDEALQSPGVNRSLFLITLERCFQVLNALECVEVLGRVLRGSSGSFLQPDITERLPQDLHEDAFKNLSAVFKDLYDQTSAHTQRALYSWMTGILRTPFNVTDGSVSWVSAEKLWILGRYMVHLSFEEIMNISPIEIGLFISYDNATKQLDMVYDITPELAQAFLERIRCSSFDVRNISTIHRLGLLVCFYDGLELLDATLAQVLLHQMLKCSRLRGFQAGVQKLKANLLDIATENQTLNETLGSLSDAVVGLTSSQLESLSSDAVHSAISTLNQVTGWGRSQIVILSAKYLAQEKVLSFYNVCQMGVLLAGVGTQAFYSMDHKDLWQVLRSPLSQDMSDLSPVQQQGVLGKLMEAEDATSGIAEVPRALFKEVSLYDLWKESRFNATVLKAKELRRSQALFLYEFLGKTTERPEELLSAGQLVKGVPCSHIDAMSDHLFLALFQYFDNNFSLLSPDQVNCLAWKYWEVSRSSMPPFLLATLPSRFLSSIPPSRCVRFLISLGKRRLETLVLDSDKRSVVVRKVQQCLDGVIADEYTVDIVGHLLCHLPASFIERGISPRAWAAALHGLRSCTALSSEQKAAVRVRLLEQWGPPENWTAETTKDLAPFLAFFSGDELHTVATKFPEILQQTASKMVGVLLPKEFLWAVFESVQNSSNESPSFDPTFGCHGVVTPSSDDIFKLAEANACWDPEVLLCMEEDTFIRNVELLGAVKGFSRAQLMALKEKAIQVWDLPSRWKEHHIVSLGRIALALSESELEQLDLSSIDTVASLGQQTEWTPGQAKSILQAFLEDSGYGIQDLKSFHLVGFGPTLCAMDPTEIQLIKTSEFRAVVARIGTLFCSTPVLAGFKKKAEVVFGRPTEWTSSILQELGTIAAGITKAELRMLNKELMTYFQPSAIRCLPGEVFKELSTEQIASLGPQNAASVTHSQRLQLSSAQLQSLQRALDGAKTHSWQTDPLSSSPTWPASTGSPTGEPASQALWLGCTLLLLTAKS

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
E9PVT3E9PVT3_MOUSEOtoa209
E9PWK6E9PWK6_MOUSEOtoa11
E9Q5L1E9Q5L1_MOUSEOtoa17
A0A140LIX3A0A140LIX3_MOUSEOtoa70
A0A140LIF2A0A140LIF2_MOUSEOtoa68

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY055122
EMBL· GenBank· DDBJ
AAL27794.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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