The mouse Clock locus: sequence and comparative analysis of 204 kb from mouse chromosome 5.Wilsbacher L.D., Sangoram A.M., Antoch M.P., Takahashi J.S.View abstractCited forNUCLEOTIDE SEQUENCEStrainB6C3F1CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenome Res. 10:1928-1940 (2000)Cited in42Mapped to14
No title available.Resuehr D., Olcese J.M.Cited forNUCLEOTIDE SEQUENCEStrainB6C3F1CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to EMBL/GenBank/DDBJ databases (JUN-2002)Cited in1
A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock.Jin X., Shearman L.P., Weaver D.R., Zylka M.J., de Vries G.J., Reppert S.M.View abstractCategoriesFunctionSourceMGI: 99698PubMedEurope PMCCell 96:57-68 (1999)Mapped to36
Molecular bases for circadian clocks.Dunlap J.C.CategoriesFunction, SequencesSourceMGI: 99698PubMedEurope PMCCell 96:271-290 (1999)Mapped to46
Clock photoreceptor shared by plants and animals.Barinaga M.CategoriesFunctionSourceMGI: 99698PubMedEurope PMCScience 282:1628-1630 (1998)Mapped to13
Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-ARTNL/BMAL1-induced transcription.Sangoram A.M., Saez L., Antoch M.P., Gekakis N., Staknis D., Whiteley A., Fruechte E.M., Vitaterna M.H., Shimomura K.[...], Takahashi J.S.View abstractCategoriesInteractionSourceMGI: 99698PubMedEurope PMCNeuron 21:1101-1113 (1998)Cited in4Mapped to25
Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock.Takahata S., Sogawa K., Kobayashi A., Ema M., Mimura J., Ozaki N., Fujii-Kuriyama Y.View abstractCategoriesSequencesSourceMGI: 99698PubMedEurope PMCBiochem. Biophys. Res. Commun. 248:789-794 (1998)Cited in1Mapped to37
Role of the CLOCK protein in the mammalian circadian mechanism.Gekakis N., Staknis D., Nguyen H.B., Davis F.C., Wilsbacher L.D., King D.P., Takahashi J.S., Weitz C.J.View abstractCategoriesInteractionSourceMGI: 99698PubMedEurope PMCScience 280:1564-1569 (1998)Cited in41Mapped to22
The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit.King D.P., Vitaterna M.H., Chang A.M., Dove W.F., Pinto L.H., Turek F.W., Takahashi J.S.View abstractCategoriesSequencesSourceMGI: 99698PubMedEurope PMCGenetics 146:1049-1060 (1997)Mapped to30
Functional identification of the mouse circadian clock gene by transgenic BAC rescue.Antoch M.P., Song E.J., Chang A.M., Vitaterna M.H., Zhao Y., Wilsbacher L.D., Sangoram A.M., King D.P., Pinto L.H., Takahashi J.S.View abstractCategoriesFunction, SequencesSourceMGI: 99698PubMedEurope PMCCell 89:655-667 (1997)Cited in1Mapped to9
Positional cloning of the mouse circadian clock gene.King D.P., Zhao Y., Sangoram A.M., Wilsbacher L.D., Tanaka M., Antoch M.P., Steeves T.D.L., Vitaterna M.H., Kornhauser J.M.[...], Takahashi J.S.View abstractCategoriesSequencesSourceMGI: 99698PubMedEurope PMCCell 89:641-653 (1997)Cited in1Mapped to9
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior.Vitaterna M.H., King D.P., Chang A.M., Kornhauser J.M., Lowrey P.L., McDonald J.D., Dove W.F., Pinto L.H., Turek F.W., Takahashi J.S.View abstractCategoriesSequencesSourceMGI: 99698PubMedEurope PMCScience 264:719-725 (1994)Mapped to7
Phosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER- dependent inhibition in circadian clock of mammalian cells.Otobe Y., Jeong E.M., Ito S., Shinohara Y., Kurabayashi N., Aiba A., Fukada Y., Kim J.K., Yoshitane H.View abstractAnnotationPhosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells.CategoriesFunctionSourceGeneRif: 12753PubMedEurope PMCProc Natl Acad Sci U S A 121:e2316858121-e2316858121 (2024)Mapped to31
Oncogenic fatty acid oxidation senses circadian disruption in sleep- deficiency-enhanced tumorigenesis.Peng F., Lu J., Su K., Liu X., Luo H., He B., Wang C., Zhang X., An F.[...], Liu Q.View abstractSourceMGI: 99698PubMedEurope PMCCell Metab 36:1598-1618.e11 (2024)Mapped to16
Chronic circadian rhythm disorder induces heart failure with preserved ejection fraction-like phenotype through the Clock-sGC-cGMP-PKG1 signaling pathway.Che Y., Shimizu Y., Hayashi T., Suzuki J., Pu Z., Tsuzuki K., Narita S., Shibata R., Murohara T.View abstractAnnotationChronic circadian rhythm disorder induces heart failure with preserved ejection fraction-like phenotype through the Clock-sGC-cGMP-PKG1 signaling pathway.SourceGeneRif: 12753PubMedEurope PMCSci Rep 14:10777-10777 (2024)Mapped to7
Clock knockout in inhibitory neurons reduces predisposition to epilepsy and influences anxiety-like behaviors in mice.Deng L., Jiang H., Lin J., Xu D., Qi A., Guo Q., Li P.P., Wang X., Liu J.S.[...], Li P.View abstractAnnotationClock knockout in inhibitory neurons reduces predisposition to epilepsy and influences anxiety-like behaviors in mice.SourceGeneRif: 12753PubMedEurope PMCNeurobiol Dis 193:106457-106457 (2024)Mapped to7
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractCategoriesFunctionSourceMGI: 99698PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Sleep deprivation reduced LPS-induced IgG2b production by up-regulating BMAL1 and CLOCK expression.Xing C., Zhai B., Zhang Y., Fang Y., Zhang M., Zhang C., Wang W., Ding M., Huang X.[...], Song L.View abstractAnnotationSleep deprivation reduced LPS-induced IgG2b production by up-regulating BMAL1 and CLOCK expression.CategoriesFunctionSourceGeneRif: 12753, MGI: 99698PubMedEurope PMCBiochem Biophys Res Commun 691:149326-149326 (2024)Mapped to26
An aging-susceptible circadian rhythm controls cutaneous antiviral immunity.Kirchner S.J., Lei V., Kim P.T., Patel M., Shannon J.L., Corcoran D., Hughes D., Waters D.K., Dzirasa K.[...], Zhang J.Y.View abstractCategoriesFunctionSourceMGI: 99698PubMedEurope PMCJCI Insight 8:e171548-e171548 (2023)Mapped to22
miR34a-5p impedes CLOCK expression in chronodisruptive C57BL/6J mice and potentiates pro-atherogenic manifestations.Vyas H., Vohra A., Upadhyay K., Thounaojam M., Jadeja R., Dalvi N., Bartoli M., Devkar R.View abstractAnnotationmiR34a-5p impedes CLOCK expression in chronodisruptive C57BL/6J mice and potentiates pro-atherogenic manifestations.CategoriesFunctionSourceGeneRif: 12753PubMedEurope PMCPLoS One 18:e0283591-e0283591 (2023)Mapped to7
CPEB4-CLOCK crosstalk during temporal lobe epilepsy.de Diego-Garcia L., Brennan G.P., Auer T., Menendez-Mendez A., Parras A., Martin-Gil A., Mitra M., Olla I., Villalba-Benito L.[...], Engel T.View abstractAnnotationCPEB4-CLOCK crosstalk during temporal lobe epilepsy.CategoriesFunctionSourceGeneRif: 12753PubMedEurope PMCEpilepsia 64:2827-2840 (2023)Mapped to13
Circadian Disruption Primes Myofibroblasts for Accelerated Activation as a Mechanism Underpinning Fibrotic Progression in Non-Alcoholic Fatty Liver Disease.ID-LIVER ConsortiumJokl E., Llewellyn J., Simpson K., Adegboye O., Pritchett J., Zeef L., Donaldson I., Athwal V.S., Purssell H.[...], Piper Hanley K.View abstractCategoriesNamesSourceMGI: 99698PubMedEurope PMCCells 12:1582-1582 (2023)Mapped to7
A potential role of <i>p75NTR</i> in the regulation of circadian rhythm and incremental growth lines during tooth development.Yuan H., Xie B., Yu X., Lin C., Li M., Zhang Y., Zou X., Lu M., Zhao M., Wen X.View abstractCategoriesExpressionSourceMGI: 99698PubMedEurope PMCFront Physiol 13:981311-981311 (2022)Mapped to62
Neuronal Bmal1 regulates retinal angiogenesis and neovascularization in mice.Jidigam V.K., Sawant O.B., Fuller R.D., Wilcots K., Singh R., Lang R.A., Rao S.View abstractCategoriesFunctionSourceMGI: 99698PubMedEurope PMCCommun Biol 5:792-792 (2022)Mapped to35
The Clock gene regulates kainic acid-induced seizures through inhibiting ferroptosis in mice.Wang F., Guo L., Wu Z., Zhang T., Dong D., Wu B.View abstractAnnotationThe Clock gene regulates kainic acid-induced seizures through inhibiting ferroptosis in mice.CategoriesFunction, ExpressionSourceGeneRif: 12753PubMedEurope PMCJ Pharm Pharmacol 74:1640-1650 (2022)Mapped to7