Q8JIG0 · PA2BQ_PROFL

Function

function

PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion.

Features

Showing features for binding site, active site.

1138102030405060708090100110120130
Type
IDPosition(s)Description
Binding site43Ca2+ (UniProtKB | ChEBI)
Binding site45Ca2+ (UniProtKB | ChEBI)
Binding site47Ca2+ (UniProtKB | ChEBI)
Active site63
Binding site64Ca2+ (UniProtKB | ChEBI)
Active site105

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functioncalcium ion binding
Molecular Functioncalcium-dependent phospholipase A2 activity
Molecular Functionphospholipid binding
Molecular Functiontoxin activity
Biological Processarachidonic acid secretion
Biological Processlipid catabolic process
Biological Processphospholipid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Basic phospholipase A2 PLA-B'
  • EC number
  • Short names
    svPLA2
  • Alternative names
    • Phosphatidylcholine 2-acylhydrolase

Organism names

Accessions

  • Primary accession
    Q8JIG0

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-16
ChainPRO_000002295617-138Basic phospholipase A2 PLA-B'
Disulfide bond42↔131
Disulfide bond44↔60
Disulfide bond59↔111
Disulfide bond65↔138
Disulfide bond66↔104
Disulfide bond73↔97
Disulfide bond91↔102

Keywords

Expression

Tissue specificity

Expressed by the venom gland.

Structure

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    138
  • Mass (Da)
    15,703
  • Last updated
    2002-10-01 v1
  • Checksum
    CBDE540581DD2F10
MRTLWITAVLLVGVEGHLLQFRKMIKKMTGKEPIVSYAFYGCYCGKGGRGKPKDATDRCCFVHDCCYGKVTGCDPKWDYYTYSSENGDIVCEGDNPCTKEVCECDKAAAICFRDNLKTYKKRYMTFPDIFCTDPTEKC

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB087496
EMBL· GenBank· DDBJ
BAC02719.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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