Q8INH6 · Q8INH6_DROME
- ProteinFI18373p1
- GeneCG8775
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1025 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 276 | substrate | ||||
Sequence: E | ||||||
Binding site | 412-416 | substrate | ||||
Sequence: GAMEN | ||||||
Binding site | 448 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Active site | 449 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 452 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 471 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: E | ||||||
Site | 534 | Transition state stabilizer | ||||
Sequence: Y | ||||||
Binding site | 947 | substrate | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | extracellular space | |
Cellular Component | membrane | |
Cellular Component | plasma membrane | |
Cellular Component | side of membrane | |
Molecular Function | metalloaminopeptidase activity | |
Molecular Function | peptide binding | |
Molecular Function | zinc ion binding | |
Biological Process | peptide catabolic process | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ8INH6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Lipid-anchor, GPI-anchor
Membrane ; Lipid-anchor, GPI-anchor
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 35-59 | Helical | ||||
Sequence: ILTLAAFCVFLLVLCGFLLGALVYV |
Keywords
- Cellular component
PTM/Processing
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-26 | Disordered | ||||
Sequence: MYAAKNVRPRSSLSTDDNHRIKDTNR | ||||||
Compositional bias | 12-26 | Basic and acidic residues | ||||
Sequence: SLSTDDNHRIKDTNR | ||||||
Domain | 149-340 | Aminopeptidase N-like N-terminal | ||||
Sequence: KPSKYRLHLRPDLERKNYSGNISISLQVLEPIAFIPVHVKQLNVSTVEVKRLDESGAPLKDITPTLTFAHPEFEYWVTEFEQPLEAGNYSLLLNFTGSLVDRITGMYQSSYLDKLKNRSRSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVASEYVDGDITEVTFAETVPMSTYL | ||||||
Domain | 376-595 | Peptidase M1 membrane alanine aminopeptidase | ||||
Sequence: YALDTAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDESTSSSVNKQRVAIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLEYKGVKQMHPEWDMDNQFVIEELHPVLTIDATLASHPIVKSIESPAEITEYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVRHIYSTATTEDYLTAVEEEEGLEFDVKQIMQTW | ||||||
Domain | 676-994 | ERAP1-like C-terminal | ||||
Sequence: WIKINTNQVGYYRVNYGSEQWAELISALKNSRETFSTADRAHLLNDANTLAAAGQLNYSVALDLISYLESEQDYVPWSVGTSALATLRNRVYYTDLYTNYTTYARKLLTPIVEKVTFTVAADHLENRLRIKVLSSACSLGHESSLQQAVTLFNQWLASPETRPNPDIRDVVYYYGLQQVNTEAAWDQVWKLYLDESDAQEKLKLMNCLTAVQVPWLLQRYINWAWDESNVRRQDYFTLLGYISTNPVGQSLVWDYVRENWEKLVDRFGINERTLGRLIPTITARFSTETKLEEMQQFFAKYPEAGAGTAARQQALEAVK |
Sequence similarities
Belongs to the peptidase M1 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,025
- Mass (Da)116,386
- Last updated2003-03-01 v1
- ChecksumFCED3F1C908CBC2F
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 12-26 | Basic and acidic residues | ||||
Sequence: SLSTDDNHRIKDTNR |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014297 EMBL· GenBank· DDBJ | AAN13553.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT133181 EMBL· GenBank· DDBJ | AFA28422.1 EMBL· GenBank· DDBJ | mRNA |