Q8I5A0 · Q8I5A0_PLAF7

Function

Miscellaneous

The active site is a redox-active disulfide bond.

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site, active site.

151250100150200250300350400450500
Type
IDPosition(s)Description
Binding site72FAD (UniProtKB | ChEBI)
Binding site136FAD (UniProtKB | ChEBI)
Binding site164-166FAD (UniProtKB | ChEBI)
Binding site218-225NAD+ (UniProtKB | ChEBI)
Binding site241NAD+ (UniProtKB | ChEBI)
Binding site310NAD+ (UniProtKB | ChEBI)
Binding site352FAD (UniProtKB | ChEBI)
Binding site358-361FAD (UniProtKB | ChEBI)
Active site491Proton acceptor

GO annotations

AspectTerm
Cellular Componentmitochondrial matrix
Cellular Componentmitochondrion
Cellular Componentoxoglutarate dehydrogenase complex
Molecular Functioncatalytic activity
Molecular Functiondihydrolipoyl dehydrogenase activity
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionprotein homodimerization activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dihydrolipoyl dehydrogenase
  • EC number

Gene names

    • ORF names
      PF3D7_1232200

Organism names

  • Taxonomic identifier
  • Strain
    • Isolate 3D7
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Laverania)

Accessions

  • Primary accession
    Q8I5A0

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond63↔68Redox-active

Keywords

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain25-367FAD/NAD(P)-binding
Domain393-501Pyridine nucleotide-disulphide oxidoreductase dimerisation

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    512
  • Mass (Da)
    57,228
  • Last updated
    2009-09-22 v2
  • Checksum
    50F2FC7739E34E4A
MNSVIFRAHCFFQPLRRCFSTKKDYDVIVIGGGPGGYVCSIRCAQNKLNVLNVNEDKKLGGTCLNRGCIPSKSLLHISHNYYEAKTRFKECGILVDNVKLDIETMHKHKNKCMGNLSDGINFLYKKNNVNHIIGHGSLVDEHTVLIKTEKEEKKVTAERIVIATGSKPIEIPLKKLNDNNFNDADNVNDILEYDHEIIQNSDDILNFKKVPHNISIIGGGVIGLEIGSVFSKLGSDVTVFEYNERLCGFLDADVSKVLQKTLEKIKMKFVFNTSVIGGNIENNQAALFAKNKKTNEIKKTTSEIVLICIGRKANFDNLNLHLLNIELNKNKKIPVDEYFNVIAQPTIKAIGDAIDGPMLAHKAEEEGYLLANILFDELKNNKKKKAHINYDLVPSVIYTHPEVATVGYNEAKCKELNMNFKSVSFPFAANSRSRTIDDYDGLIKLIVEKDTNRILGSQIIGNNASDLILPLSIYVANNGSSKSLSKIIYAHPTFSEVIKEVALQSFDKPIHM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LN999947
EMBL· GenBank· DDBJ
CZT99481.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp