Q8GZ52 · AB30G_ARATH
- ProteinABC transporter G family member 30
- GeneABCG30
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1400 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Together with ABCG40, import into the embryo the abscisic acid (ABA) delivered from the endosperm via ABCG25 and ABCG31-mediated export to suppress radicle extension and subsequent embryonic growth (PubMed:26334616).
Involved in root secretion of phytochemicals (phenolics and sugars) which regulate soil microbiota, influencing both fungal and bacterial communities (PubMed:19854857).
May be a general defense protein (By similarity).
Involved in root secretion of phytochemicals (phenolics and sugars) which regulate soil microbiota, influencing both fungal and bacterial communities (PubMed:19854857).
May be a general defense protein (By similarity).
Catalytic activity
- abscisate(out) + ATP + H2O = abscisate(in) + ADP + phosphate + H+This reaction proceeds in the forward direction.abscisate (out)CHEBI:62432
+ CHEBI:30616 + CHEBI:15377 = abscisate (in)CHEBI:62432+ CHEBI:456216 + CHEBI:43474 + CHEBI:15378
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ABC-type transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATPase-coupled transmembrane transporter activity | |
Molecular Function | efflux transmembrane transporter activity | |
Biological Process | abscisic acid transport | |
Biological Process | abscisic acid-activated signaling pathway | |
Biological Process | carbohydrate export | |
Biological Process | import into cell | |
Biological Process | intercellular transport | |
Biological Process | negative regulation of post-embryonic development | |
Biological Process | transmembrane transport |
Keywords
- Biological process
- Ligand
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameABC transporter G family member 30
- Short namesABC transporter ABCG.30 ; AtABCG30
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ8GZ52
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 510-530 | Helical | ||||
Sequence: FIYLFKSALLVFNALVTMTVF | ||||||
Transmembrane | 553-573 | Helical | ||||
Sequence: LFRLLADGLPELTLTISRLGV | ||||||
Transmembrane | 582-602 | Helical | ||||
Sequence: FYPAWAYAIPSIILKIPLSVL | ||||||
Transmembrane | 628-648 | Helical | ||||
Sequence: FLILSTFNLSCVSMFRAIAAI | ||||||
Transmembrane | 652-672 | Helical | ||||
Sequence: IIASTITGAISILVLSLFGGF | ||||||
Transmembrane | 679-699 | Helical | ||||
Sequence: MPAWLGWGFWLSPLSYAEIGL | ||||||
Transmembrane | 738-758 | Helical | ||||
Sequence: TAFGALVGFVLFFNALYVLAL | ||||||
Transmembrane | 1144-1164 | Helical | ||||
Sequence: HNITRIVFILLDSTLCGLLFW | ||||||
Transmembrane | 1179-1199 | Helical | ||||
Sequence: IFGSMYTLVVFPGMNNCAAVI | ||||||
Transmembrane | 1228-1248 | Helical | ||||
Sequence: VLIEVPYSLLQSLLCTIIVYP | ||||||
Transmembrane | 1263-1283 | Helical | ||||
Sequence: LYSIFCSLLIFNYSGMLMVAL | ||||||
Transmembrane | 1289-1309 | Helical | ||||
Sequence: MAVTLRSSFFSMLNLFAGFVI | ||||||
Transmembrane | 1317-1337 | Helical | ||||
Sequence: WWIWMYYLSPTSWVLEGLLSS | ||||||
Transmembrane | 1372-1392 | Helical | ||||
Sequence: VVAFVLIAYPIIVATLFAFFM |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Early seeds germination on imbibition without stratification, and reduced abscisic acid (ABA)-mediated inhibition of stratified seeds germination (PubMed:26334616).
Altered root exudation of phytochemicals, with increased phenolics (e.g. benzoic acid, salicylic acid, syringic acid, tartaric acid, lactic acid, alpha-linolenic acid, cyanidin, sinapoyl malate, valine and indole 3-acetic acid) and decreased sugars levels (e.g. raffinose, glucose, fructose and mannitol), leading to an overhaul of natural soil microbiota, including both fungal and bacterial communities; this phenotype is associated with an up-regulation of some genes involved in biosynthesis and transport of secondary metabolites, but the down-regulation of some sugar transporters (PubMed:19854857).
Altered root exudation of phytochemicals, with increased phenolics (e.g. benzoic acid, salicylic acid, syringic acid, tartaric acid, lactic acid, alpha-linolenic acid, cyanidin, sinapoyl malate, valine and indole 3-acetic acid) and decreased sugars levels (e.g. raffinose, glucose, fructose and mannitol), leading to an overhaul of natural soil microbiota, including both fungal and bacterial communities; this phenotype is associated with an up-regulation of some genes involved in biosynthesis and transport of secondary metabolites, but the down-regulation of some sugar transporters (PubMed:19854857).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 175 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000234629 | 1-1400 | ABC transporter G family member 30 | |||
Sequence: MIQTGEEDEEKATSLEVEFASGNGVDDEEELRLQWATVERLPTFKRVTTALLARDEVSGKGRVIDVTRLEGAERRLLIEMLVKQIEDDNLRLLRKIRKRIDKVGIELPTVEVRFNNLSVEAECQVIHGKPIPTLWNTIKGLLSEFICSKKETKIGILKGVSGIVRPGRMTLLLGPPGCGKTTLLQALSGKFSDSVKVGGEVCYNGCSLSEFIPEKTSSYISQNDLHIPELSVRETLDFSACCQGIGSRMEIMKEISRMEKLQEIIPDPAVDAYMKATSVEGLKNNLQTDYILKILGLDICADTRVGDATRPGISGGEKRRLTTGELVVGPATTLFMDEISNGLDSSTTFQIVSCLQQLAHIAEATILISLLQPAPETFELFDDVILMGEGKIIYHAPRADICRFFEEFGFKCPERKGVADFLQEIMSKKDQEQYWCHRDKPYSYISVDSFINKFKESNLGLLLKEELSKPFNKSQTRKDGLCYKKYSLGKWEMLKACSRREFLLMKRNSFIYLFKSALLVFNALVTMTVFLQVGATTDSLHGNYLMGSLFTALFRLLADGLPELTLTISRLGVFCKQKDLYFYPAWAYAIPSIILKIPLSVLDSFIWTLLTYYVIGYSPEVKRFFLQFLILSTFNLSCVSMFRAIAAIFRTIIASTITGAISILVLSLFGGFVIPKSSMPAWLGWGFWLSPLSYAEIGLTANEFFSPRWSKVISSKTTAGEQMLDIRGLNFGRHSYWTAFGALVGFVLFFNALYVLALTYQNNPQRSRAIISHEKYSRPIEEDFKPCPKITSRAKTGKIILPFKPLTVTFQNVQYYIETPQGKTRQLLSDITGALKPGVLTSLMGVSGAGKTTLLDVLSGRKTRGIIKGEIKVGGYPKVQETFARVSGYCEQFDIHSPNITVEESLKYSAWLRLPYNIDSKTKNELVKEVLETVELDDIKDSVVGLPGISGLSIEQRKRLTIAVELVANPSIIFMDEPTTGLDARAAAIVMRAVKNVAETGRTVVCTIHQPSIDIFETFDELILMKNGGQLVYYGPPGQNSSKVIEYFESFSGLPKIQKNCNPATWILDITSKSAEEKLGIDFSQSYKDSTLYKQNKMVVEQLSSASLGSEALRFPSQFSQTAWVQLKACLWKQHYSYWRNPSHNITRIVFILLDSTLCGLLFWQKAEDINNQQDLISIFGSMYTLVVFPGMNNCAAVINFIAAERNVFYRERFARMYSSWAYSFSQVLIEVPYSLLQSLLCTIIVYPTIGYHMSVYKMFWSLYSIFCSLLIFNYSGMLMVALTPNIHMAVTLRSSFFSMLNLFAGFVIPKQKIPKWWIWMYYLSPTSWVLEGLLSSQYGDVDKEILVFGEKKRVSAFLEDYFGYKHESLAVVAFVLIAYPIIVATLFAFFMSKLSFQKK | ||||||
Glycosylation | 116 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 472 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 899 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 1040 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 141-414 | ABC transporter 1 | ||||
Sequence: LLSEFICSKKETKIGILKGVSGIVRPGRMTLLLGPPGCGKTTLLQALSGKFSDSVKVGGEVCYNGCSLSEFIPEKTSSYISQNDLHIPELSVRETLDFSACCQGIGSRMEIMKEISRMEKLQEIIPDPAVDAYMKATSVEGLKNNLQTDYILKILGLDICADTRVGDATRPGISGGEKRRLTTGELVVGPATTLFMDEISNGLDSSTTFQIVSCLQQLAHIAEATILISLLQPAPETFELFDDVILMGEGKIIYHAPRADICRFFEEFGFKCPE | ||||||
Domain | 492-704 | ABC transmembrane type-2 1 | ||||
Sequence: EMLKACSRREFLLMKRNSFIYLFKSALLVFNALVTMTVFLQVGATTDSLHGNYLMGSLFTALFRLLADGLPELTLTISRLGVFCKQKDLYFYPAWAYAIPSIILKIPLSVLDSFIWTLLTYYVIGYSPEVKRFFLQFLILSTFNLSCVSMFRAIAAIFRTIIASTITGAISILVLSLFGGFVIPKSSMPAWLGWGFWLSPLSYAEIGLTANEF | ||||||
Domain | 808-1053 | ABC transporter 2 | ||||
Sequence: VTFQNVQYYIETPQGKTRQLLSDITGALKPGVLTSLMGVSGAGKTTLLDVLSGRKTRGIIKGEIKVGGYPKVQETFARVSGYCEQFDIHSPNITVEESLKYSAWLRLPYNIDSKTKNELVKEVLETVELDDIKDSVVGLPGISGLSIEQRKRLTIAVELVANPSIIFMDEPTTGLDARAAAIVMRAVKNVAETGRTVVCTIHQPSIDIFETFDELILMKNGGQLVYYGPPGQNSSKVIEYFESFSG | ||||||
Domain | 1125-1339 | ABC transmembrane type-2 2 | ||||
Sequence: VQLKACLWKQHYSYWRNPSHNITRIVFILLDSTLCGLLFWQKAEDINNQQDLISIFGSMYTLVVFPGMNNCAAVINFIAAERNVFYRERFARMYSSWAYSFSQVLIEVPYSLLQSLLCTIIVYPTIGYHMSVYKMFWSLYSIFCSLLIFNYSGMLMVALTPNIHMAVTLRSSFFSMLNLFAGFVIPKQKIPKWWIWMYYLSPTSWVLEGLLSSQY |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q8GZ52-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length1,400
- Mass (Da)157,768
- Last updated2006-05-16 v2
- ChecksumEED12151C91EB57B
Q8GZ52-2
- Name2
- Differences from canonical
- 1-640: Missing
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8B5S3 | A0A1P8B5S3_ARATH | ABCG30 | 1321 | ||
A0A1P8B5R0 | A0A1P8B5R0_ARATH | ABCG30 | 1324 |
Sequence caution
Features
Showing features for alternative sequence.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_018392 | 1-640 | in isoform 2 | |||
Sequence: Missing |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
Z97338 EMBL· GenBank· DDBJ | CAB10301.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
Z97338 EMBL· GenBank· DDBJ | CAB45997.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AL161540 EMBL· GenBank· DDBJ | CAB78564.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AL161540 EMBL· GenBank· DDBJ | CAB78565.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002687 EMBL· GenBank· DDBJ | AEE83571.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | ANM66937.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK117203 EMBL· GenBank· DDBJ | BAC41879.1 EMBL· GenBank· DDBJ | mRNA | ||
BK001000 EMBL· GenBank· DDBJ | DAA00869.1 EMBL· GenBank· DDBJ | Genomic DNA |