Q8GZ52 · AB30G_ARATH

Function

function

Together with ABCG40, import into the embryo the abscisic acid (ABA) delivered from the endosperm via ABCG25 and ABCG31-mediated export to suppress radicle extension and subsequent embryonic growth (PubMed:26334616).
Involved in root secretion of phytochemicals (phenolics and sugars) which regulate soil microbiota, influencing both fungal and bacterial communities (PubMed:19854857).
May be a general defense protein (By similarity).

Catalytic activity

Features

Showing features for binding site.

114001002003004005006007008009001,0001,1001,2001,3001,400
TypeIDPosition(s)Description
Binding site174-181ATP 1 (UniProtKB | ChEBI)
Binding site845-852ATP 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionABC-type transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATPase-coupled transmembrane transporter activity
Molecular Functionefflux transmembrane transporter activity
Biological Processabscisic acid transport
Biological Processabscisic acid-activated signaling pathway
Biological Processcarbohydrate export
Biological Processimport into cell
Biological Processintercellular transport
Biological Processnegative regulation of post-embryonic development
Biological Processtransmembrane transport

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    ABC transporter G family member 30
  • Short names
    ABC transporter ABCG.30
    ; AtABCG30
  • Alternative names
    • Pleiotropic drug resistance protein 2
      (AtPDR2
      )

Gene names

    • Name
      ABCG30
    • Synonyms
      PDR2
    • ORF names
      dl3660w/dl3655w
      , FCAALL.241
    • Ordered locus names
      At4g15230/At4g15220

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8GZ52
  • Secondary accessions
    • O23376
    • O23377
    • Q7PC89

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane510-530Helical
Transmembrane553-573Helical
Transmembrane582-602Helical
Transmembrane628-648Helical
Transmembrane652-672Helical
Transmembrane679-699Helical
Transmembrane738-758Helical
Transmembrane1144-1164Helical
Transmembrane1179-1199Helical
Transmembrane1228-1248Helical
Transmembrane1263-1283Helical
Transmembrane1289-1309Helical
Transmembrane1317-1337Helical
Transmembrane1372-1392Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Early seeds germination on imbibition without stratification, and reduced abscisic acid (ABA)-mediated inhibition of stratified seeds germination (PubMed:26334616).
Altered root exudation of phytochemicals, with increased phenolics (e.g. benzoic acid, salicylic acid, syringic acid, tartaric acid, lactic acid, alpha-linolenic acid, cyanidin, sinapoyl malate, valine and indole 3-acetic acid) and decreased sugars levels (e.g. raffinose, glucose, fructose and mannitol), leading to an overhaul of natural soil microbiota, including both fungal and bacterial communities; this phenotype is associated with an up-regulation of some genes involved in biosynthesis and transport of secondary metabolites, but the down-regulation of some sugar transporters (PubMed:19854857).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 175 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00002346291-1400ABC transporter G family member 30
Glycosylation116N-linked (GlcNAc...) asparagine
Glycosylation472N-linked (GlcNAc...) asparagine
Glycosylation899N-linked (GlcNAc...) asparagine
Glycosylation1040N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Confined to roots (PubMed:12430018).
In seeds, mainly expressed in the embryo and, to a lesser extent, in the endosperm (PubMed:26334616).

Induction

Repressed by cold/dark treatment.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain141-414ABC transporter 1
Domain492-704ABC transmembrane type-2 1
Domain808-1053ABC transporter 2
Domain1125-1339ABC transmembrane type-2 2

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q8GZ52-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    1,400
  • Mass (Da)
    157,768
  • Last updated
    2006-05-16 v2
  • Checksum
    EED12151C91EB57B
MIQTGEEDEEKATSLEVEFASGNGVDDEEELRLQWATVERLPTFKRVTTALLARDEVSGKGRVIDVTRLEGAERRLLIEMLVKQIEDDNLRLLRKIRKRIDKVGIELPTVEVRFNNLSVEAECQVIHGKPIPTLWNTIKGLLSEFICSKKETKIGILKGVSGIVRPGRMTLLLGPPGCGKTTLLQALSGKFSDSVKVGGEVCYNGCSLSEFIPEKTSSYISQNDLHIPELSVRETLDFSACCQGIGSRMEIMKEISRMEKLQEIIPDPAVDAYMKATSVEGLKNNLQTDYILKILGLDICADTRVGDATRPGISGGEKRRLTTGELVVGPATTLFMDEISNGLDSSTTFQIVSCLQQLAHIAEATILISLLQPAPETFELFDDVILMGEGKIIYHAPRADICRFFEEFGFKCPERKGVADFLQEIMSKKDQEQYWCHRDKPYSYISVDSFINKFKESNLGLLLKEELSKPFNKSQTRKDGLCYKKYSLGKWEMLKACSRREFLLMKRNSFIYLFKSALLVFNALVTMTVFLQVGATTDSLHGNYLMGSLFTALFRLLADGLPELTLTISRLGVFCKQKDLYFYPAWAYAIPSIILKIPLSVLDSFIWTLLTYYVIGYSPEVKRFFLQFLILSTFNLSCVSMFRAIAAIFRTIIASTITGAISILVLSLFGGFVIPKSSMPAWLGWGFWLSPLSYAEIGLTANEFFSPRWSKVISSKTTAGEQMLDIRGLNFGRHSYWTAFGALVGFVLFFNALYVLALTYQNNPQRSRAIISHEKYSRPIEEDFKPCPKITSRAKTGKIILPFKPLTVTFQNVQYYIETPQGKTRQLLSDITGALKPGVLTSLMGVSGAGKTTLLDVLSGRKTRGIIKGEIKVGGYPKVQETFARVSGYCEQFDIHSPNITVEESLKYSAWLRLPYNIDSKTKNELVKEVLETVELDDIKDSVVGLPGISGLSIEQRKRLTIAVELVANPSIIFMDEPTTGLDARAAAIVMRAVKNVAETGRTVVCTIHQPSIDIFETFDELILMKNGGQLVYYGPPGQNSSKVIEYFESFSGLPKIQKNCNPATWILDITSKSAEEKLGIDFSQSYKDSTLYKQNKMVVEQLSSASLGSEALRFPSQFSQTAWVQLKACLWKQHYSYWRNPSHNITRIVFILLDSTLCGLLFWQKAEDINNQQDLISIFGSMYTLVVFPGMNNCAAVINFIAAERNVFYRERFARMYSSWAYSFSQVLIEVPYSLLQSLLCTIIVYPTIGYHMSVYKMFWSLYSIFCSLLIFNYSGMLMVALTPNIHMAVTLRSSFFSMLNLFAGFVIPKQKIPKWWIWMYYLSPTSWVLEGLLSSQYGDVDKEILVFGEKKRVSAFLEDYFGYKHESLAVVAFVLIAYPIIVATLFAFFMSKLSFQKK

Q8GZ52-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8B5S3A0A1P8B5S3_ARATHABCG301321
A0A1P8B5R0A0A1P8B5R0_ARATHABCG301324

Sequence caution

The sequence CAB10301.1 differs from that shown. Reason: Erroneous gene model prediction Was originally thought to correspond to two different genes At4g15220 and At4g15230.
The sequence CAB45997.1 differs from that shown. Reason: Erroneous gene model prediction Was originally thought to correspond to two different genes At4g15220 and At4g15230.
The sequence CAB78564.1 differs from that shown. Reason: Erroneous gene model prediction Was originally thought to correspond to two different genes At4g15220 and At4g15230.
The sequence CAB78565.1 differs from that shown. Reason: Erroneous gene model prediction Was originally thought to correspond to two different genes At4g15220 and At4g15230.

Features

Showing features for alternative sequence.

TypeIDPosition(s)Description
Alternative sequenceVSP_0183921-640in isoform 2

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z97338
EMBL· GenBank· DDBJ
CAB10301.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
Z97338
EMBL· GenBank· DDBJ
CAB45997.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AL161540
EMBL· GenBank· DDBJ
CAB78564.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AL161540
EMBL· GenBank· DDBJ
CAB78565.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002687
EMBL· GenBank· DDBJ
AEE83571.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
ANM66937.1
EMBL· GenBank· DDBJ
Genomic DNA
AK117203
EMBL· GenBank· DDBJ
BAC41879.1
EMBL· GenBank· DDBJ
mRNA
BK001000
EMBL· GenBank· DDBJ
DAA00869.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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