Q8GV50 · PLA2D_ARATH

Function

function

PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Releases lysophospholipids (LPLs) and free fatty acids (FFAs) from membrane phospholipids in response to hormones and other external stimuli. Plays a role in pollen development and germination and tube growth.

Miscellaneous

The enzyme has a slight preference for phosphatidylethanolamine over phosphatidylcholine.

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )
Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site48Ca2+ (UniProtKB | ChEBI)
Binding site50Ca2+ (UniProtKB | ChEBI)
Binding site53Ca2+ (UniProtKB | ChEBI)
Active site72
Binding site73Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentextracellular region
Molecular Functioncalcium ion binding
Molecular Functionphospholipase A2 activity
Biological Processarachidonic acid secretion
Biological Processlipid catabolic process
Biological Processphospholipid metabolic process
Biological Processpollen development
Biological Processpollen germination
Biological Processpollen tube growth

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospholipase A2-delta
  • EC number
  • Alternative names
    • Secretory phospholipase A2-delta (AtsPLA2-delta)

Gene names

    • Name
      PLA2-DELTA
    • ORF names
      F17A13.290
    • Ordered locus names
      At4g29470

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8GV50
  • Secondary accessions
    • Q9M0D6

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-25
ChainPRO_000041756426-191Phospholipase A2-delta
Disulfide bond29↔56
Disulfide bond33↔62
Disulfide bond38↔115
Disulfide bond49↔69
Disulfide bond68↔93
Disulfide bond75↔86

Keywords

Proteomic databases

Expression

Tissue specificity

Specifically expressed in flowers but at a low level. Detected specifically in the pollen.

Developmental stage

Expressed during pollen germination and tube growth.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region161-191Disordered
Compositional bias165-191Polar residues

Sequence similarities

Belongs to the phospholipase A2 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    191
  • Mass (Da)
    20,617
  • Last updated
    2003-03-01 v1
  • Checksum
    3E6F729E288CB149
MIRGGALTHVALGLTVFLLLAVVHSQEKCSKTCIAQKCNVLGIRYGKYCGIGYFGCPGEPPCDDLDDCCMTHDNCVDLKGMTYVDCHKQFQRCVNELKQSIQESNNQKVGFSKECPYSTVIPTVYRGMNYGIFFSGIGNIIIPKKPASAGPVVEVDLARSKADTKDGLGTNQGPQTKDGSKVSVPMNPSPS

Sequence caution

The sequence CAB79705.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias165-191Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY148347
EMBL· GenBank· DDBJ
AAN63045.1
EMBL· GenBank· DDBJ
mRNA
AL161575
EMBL· GenBank· DDBJ
CAB79705.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002687
EMBL· GenBank· DDBJ
AEE85635.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
ANM66586.1
EMBL· GenBank· DDBJ
Genomic DNA
AB493706
EMBL· GenBank· DDBJ
BAH30544.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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