Q8GUN5 · PHL1_ARATH

Function

function

Transcription factor acting as central integrator of phosphate starvation responses (PubMed:20838596).
Regulates FER1 expression upon phosphate starvation, linking iron and phosphate homeostasis (PubMed:23788639).

Features

Showing features for dna binding.

141350100150200250300350400
TypeIDPosition(s)Description
DNA binding259-284H-T-H motif

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Molecular FunctionDNA-binding transcription factor activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein PHR1-LIKE 1
  • Alternative names
    • Myb-like transcription factor 1

Gene names

    • Name
      PHL1
    • ORF names
      F3F24.100
    • Ordered locus names
      At5g29000

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8GUN5
  • Secondary accessions
    • B3H6E5
    • F4KBG7
    • Q8LEY3

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

No effect on phosphate starvation responsiveness, due to the redundancy with PHR1.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 41 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004181251-413Protein PHR1-LIKE 1

Proteomic databases

Expression

Tissue specificity

Expressed in shoots and roots.

Induction

Not up-regulated by Pi starvation.

Gene expression databases

Interaction

Subunit

Homodimers and heterodimers (PubMed:20838596).
Interacts with MED25 (PubMed:21343311, PubMed:21536906).
Does not interact with PHL2 or PHL3 (PubMed:26586833).

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q8GUN5-2MED25 Q7XYY2-12EBI-15924466, EBI-15924435

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain, motif.

TypeIDPosition(s)Description
Region171-196Disordered
Compositional bias176-191Polar residues
Region208-233Disordered
Domain228-288HTH myb-type
Region322-342Coiled coil
Motif335-340LHEQLE
Compositional bias363-381Polar residues
Region363-413Disordered

Sequence similarities

Belongs to the MYB-CC family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoforms

Align isoforms (3)
  • Sequence status
    Complete

This entry describes 3 isoforms produced by Alternative splicing.

Q8GUN5-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    413
  • Mass (Da)
    46,221
  • Last updated
    2003-03-01 v1
  • Checksum
    739BAB69CD76C047
MTLANDFGYSTAMSSSYSALHTSVEDRYHKLPNSFWVSSGQELMNNPVPCQSVSGGNSGGYLFPSSSGYCNVSAVLPHGRNLQNQPPVSTVPRDRLAMQDCPLIAQSSLINHHPQEFIDPLHEFFDFSDHVPVQNLQAESSGVRVDSSVELHKKSEWQDWADQLISVDDGSEPNWSELLGDSSSHNPNSEIPTPFLDVPRLDITANQQQQMVSSEDQLSGRNSSSSVATSKQRMRWTPELHEAFVEAVNQLGGSERATPKAVLKLLNNPGLTIYHVKSHLQKYRTARYKPETSEVTGEPQEKKMTSIEDIKSLDMKTSVEITQALRLQMEVQKRLHEQLEIQRSLQLQIEKQGRYLQMMFEKQQKIQDNKSSSSEASPKQCNGSFAEVEVGLETLTGDQNESASASRKRVRED

Q8GUN5-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Q8GUN5-3

  • Name
    3
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Features

Showing features for alternative sequence, sequence conflict, compositional bias.

TypeIDPosition(s)Description
Alternative sequenceVSP_0439941-43in isoform 2
Sequence conflict26in Ref. 4; AAM61707
Compositional bias176-191Polar residues
Alternative sequenceVSP_043995298-311in isoform 3
Alternative sequenceVSP_043996312-413in isoform 3
Compositional bias363-381Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC018632
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002688
EMBL· GenBank· DDBJ
AED93856.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED93857.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED93858.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED93859.1
EMBL· GenBank· DDBJ
Genomic DNA
BT002344
EMBL· GenBank· DDBJ
AAN86177.1
EMBL· GenBank· DDBJ
mRNA
AY085154
EMBL· GenBank· DDBJ
AAM61707.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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