Q8GJ13 · Q8GJ13_ECOLX
- ProteinCytolethal distending toxin subunit A
- GenecdtA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids258 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
CDTs are cytotoxins.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | cell outer membrane | |
Molecular Function | carbohydrate binding | |
Molecular Function | toxin activity |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytolethal distending toxin subunit A
- Short namesCDT A
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionQ8GJ13
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell outer membrane ; Lipid-anchor
Membrane ; Lipid-anchor
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 33-61 | Disordered | ||||
Sequence: PKVFPPQVEGGPTIPSPDEPGLPLPGAGP | ||||||
Compositional bias | 40-61 | Pro residues | ||||
Sequence: VEGGPTIPSPDEPGLPLPGAGP |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length258
- Mass (Da)27,845
- Last updated2003-03-01 v1
- Checksum4F621BDA373F64FA
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 40-61 | Pro residues | ||||
Sequence: VEGGPTIPSPDEPGLPLPGAGP |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY365042 EMBL· GenBank· DDBJ | AAR12197.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY365043 EMBL· GenBank· DDBJ | AAR12200.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB472839 EMBL· GenBank· DDBJ | BAH72979.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB472870 EMBL· GenBank· DDBJ | BAH78166.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839651 EMBL· GenBank· DDBJ | BAO73989.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839652 EMBL· GenBank· DDBJ | BAO73992.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839653 EMBL· GenBank· DDBJ | BAO73995.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839654 EMBL· GenBank· DDBJ | BAO73998.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839655 EMBL· GenBank· DDBJ | BAO74001.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839656 EMBL· GenBank· DDBJ | BAO74004.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839657 EMBL· GenBank· DDBJ | BAO74007.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839658 EMBL· GenBank· DDBJ | BAO74010.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839659 EMBL· GenBank· DDBJ | BAO74013.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839661 EMBL· GenBank· DDBJ | BAO74019.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839662 EMBL· GenBank· DDBJ | BAO74022.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839663 EMBL· GenBank· DDBJ | BAO74025.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839667 EMBL· GenBank· DDBJ | BAO74037.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839668 EMBL· GenBank· DDBJ | BAO74040.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB839669 EMBL· GenBank· DDBJ | BAO74043.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AJ508930 EMBL· GenBank· DDBJ | CAD48849.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AASCJS010000020 EMBL· GenBank· DDBJ | EFA9846913.1 EMBL· GenBank· DDBJ | Genomic DNA |