Q8EY52 · Q8EY52_LEPIN
- Protein1,4-dihydroxy-6-naphtoate synthase
- GenemqnD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids274 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
Catalytic activity
- cyclic dehypoxanthinylfutalosinate = 1,4-dihydroxy-6-naphthoate + dihydroxyacetone
Pathway
Quinol/quinone metabolism; menaquinone biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 54-56 | substrate | ||||
Sequence: KLS | ||||||
Binding site | 108-109 | substrate | ||||
Sequence: TA | ||||||
Active site | 147 | Proton acceptor | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | carbon-carbon lyase activity | |
Biological Process | menaquinone biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name1,4-dihydroxy-6-naphtoate synthase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Spirochaetota > Spirochaetia > Leptospirales > Leptospiraceae > Leptospira
Accessions
- Primary accessionQ8EY52
Proteomes
PTM/Processing
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence similarities
Belongs to the MqnA/MqnD family. MqnD subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length274
- Mass (Da)31,318
- Last updated2003-03-01 v1
- Checksum2C1C14FA4106F8F6
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE010301 EMBL· GenBank· DDBJ | AAN51564.1 EMBL· GenBank· DDBJ | Genomic DNA |