Q8EIV5 · KATG2_SHEON

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site103Transition state stabilizer
Active site107Proton acceptor
Binding site270Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase 2
  • EC number
  • Short names
    CP 2
  • Alternative names
    • Peroxidase/catalase 2

Gene names

    • Name
      katG2
    • Ordered locus names
      SO_0725

Organism names

Accessions

  • Primary accession
    Q8EIV5

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain, cross-link.

Type
IDPosition(s)Description
Signal1-27
ChainPRO_000035492128-741Catalase-peroxidase 2
Cross-link106↔229Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-255)
Cross-link229↔255Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-106)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Proteomic databases

Interaction

Subunit

Homodimer or homotetramer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    741
  • Mass (Da)
    81,256
  • Last updated
    2003-03-01 v1
  • MD5 Checksum
    3EBA3B478C4FD842DBE005C948808909
MKINTLPTLSALTLAMSLALGAGMATAQEQATGNQFWWPEKLNLSPLRQNAIESNPYGSDYRYAEAFNTLDLDAVKKDIKALMTESQDWWPADYGHYGPFFIRMAWHSAGVYRIFDGRGGAAGGQQRFEPLNSWPADNVSLDKARRLLWPIKQKYGSKLSWGDLMVLTGNVALESMGFKTFGFGGGRVDDWEAEMVNWGSEKAWLDNKRHNGKGELAKPMGATQMGLIYVNPEGPNGVPDPLASAKEIRDTFGRMAMNDEETVALIAGGHTFGKAHGAHDPAKCVGADPAAAGIEEQGLGWKNKCGKGHSEDTVTSGLEGAWSSNPTKWTMEYLTWLYTFDWVQTKSPAGHIQWTPADGKAANLVPDAHLPDKRHAPIMFTSDIALKADPIYREITTRFLKNPQEFELAFAKAWFKLTHRDLGPKARYLGADVPAEALIWQDPIPALDHPLIDNADIKALGNKILASGLTVPELVRTAWASASSFRGTDMRGGANGARIRLEPMMNWQANNPKELAKVLAKLEKVQKDFNGSLKGSKKVSLADVIVLGGSVAVEKAAKEAGVVISVPFTPGRMDATQVQTDVNSFAVLEPAADGFRNYYSKDSSLSPAEMLIERANMLNLTVPEMTVLVGGLRALDANSAGVKHGVFTDKPGVLSNDFFVNLLDMSTKWRKSDKQEGIYEGQDRNSGKLKWTATPVDLIFGSHSELRAVSEVYGAQDGQDRFIQDFVKAWNKVMNADRFDI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014299
EMBL· GenBank· DDBJ
AAN53803.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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