Q8EIV5 · KATG2_SHEON
- ProteinCatalase-peroxidase 2
- GenekatG2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids741 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
Catalytic activity
- H2O2 + AH2 = A + 2 H2O
Cofactor
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
Features
Showing features for site, active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 103 | Transition state stabilizer | |||
Active site | 107 | Proton acceptor | |||
Binding site | 270 | Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | catalase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | cellular response to hydrogen peroxide | |
Biological Process | hydrogen peroxide catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameCatalase-peroxidase 2
- EC number
- Short namesCP 2
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella
Accessions
- Primary accessionQ8EIV5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain, cross-link.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-27 | ||||
Chain | PRO_0000354921 | 28-741 | Catalase-peroxidase 2 | ||
Cross-link | 106↔229 | Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-255) | |||
Cross-link | 229↔255 | Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-106) | |||
Post-translational modification
Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length741
- Mass (Da)81,256
- Last updated2003-03-01 v1
- MD5 Checksum3EBA3B478C4FD842DBE005C948808909
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014299 EMBL· GenBank· DDBJ | AAN53803.1 EMBL· GenBank· DDBJ | Genomic DNA |