Q8E8N6 · BIOH_SHEON

Function

function

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

Pathway

Cofactor biosynthesis; biotin biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site28substrate
Active site86Nucleophile
Binding site86-87substrate
Binding site149-153substrate
Active site213
Active site240
Binding site240substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncarboxylic ester hydrolase activity
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • EC number
  • Alternative names
    • Biotin synthesis protein BioH
    • Carboxylesterase BioH

Gene names

    • Name
      bioH
    • Ordered locus names
      SO_4626

Organism names

Accessions

  • Primary accession
    Q8E8N6

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002044931-263Pimeloyl-[acyl-carrier protein] methyl ester esterase

Proteomic databases

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    263
  • Mass (Da)
    28,993
  • Last updated
    2005-08-16 v2
  • Checksum
    B0B1B3522862233D
MNATTSAHHPLHIETIGQGPDLVVIHGWGVNSAVFTPLHEQLSEYRVHYVDLPGFGLSQPIAGNLSTWIDALINNLPTNAIWAGWSLGGLVATQAAIDYPSHIKGLITIASSPCFMAREEEAWPGIPPQVLSMFGEQLGQNLPKTIERFLAIQAMGSETAKEDIKQLRDLVLARPLPDAAALTQGLDMLNQIDLRMQLSSISQPWLRIWGRLDGLVPKRVQPQMPTASHITDVMLAKASHAPFVSHRQEFLQALLPWLTQFKD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014299
EMBL· GenBank· DDBJ
AAN57586.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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