Q8DZQ2 · PYRF_STRA5

Function

function

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Features

Showing features for binding site, active site.

123320406080100120140160180200220
Type
IDPosition(s)Description
Binding site11substrate
Binding site34substrate
Binding site61-70substrate
Active site63Proton donor
Binding site117substrate
Binding site179substrate
Binding site189substrate
Binding site209substrate
Binding site210substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionorotidine-5'-phosphate decarboxylase activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Orotidine 5'-phosphate decarboxylase
  • EC number
  • Alternative names
    • OMP decarboxylase
      (OMPDCase
      ; OMPdecase
      )

Gene names

    • Name
      pyrF
    • Ordered locus names
      SAG1047

Organism names

Accessions

  • Primary accession
    Q8DZQ2

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001345851-233Orotidine 5'-phosphate decarboxylase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the OMP decarboxylase family. Type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    233
  • Mass (Da)
    25,994
  • Last updated
    2003-03-01 v1
  • Checksum
    708384FCF55E472D
MLEKCPIIALDFSDLASVTTFLEHFPKEELLFVKIGMELYYSEGPSIIRYIKSLGHRIFLDLKLHDIPNTVRSSMSVLAKLGIDMTNVHAAGGVEMMKAAREGLGKGPILLAVTQLTSTSQEQMQVDQHINLSVVDSVCHYAQKAQEAGLDGVVASAQEGMQIKKQTNEHFICLTPGIRPPQTNQLDDQKRTMTPEQARIVGADYIVVGRPITKAENPYQAYLEIKEEWNRIK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE009948
EMBL· GenBank· DDBJ
AAM99929.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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