Q8DKE4 · RNZ_THEVB
- ProteinRibonuclease Z
- Genernz
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids407 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity).
Catalytic activity
Cofactor
Note: Binds 2 Zn2+ ions.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 62 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 64 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Active site | 66 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 66 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: D | ||||||
Binding site | 67 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 139 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 210 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: D | ||||||
Binding site | 210 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: D | ||||||
Binding site | 268 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3'-tRNA processing endoribonuclease activity | |
Molecular Function | zinc ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease Z
- EC number
- Short namesRNase Z
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Acaryochloridales > Thermosynechococcaceae > Thermosynechococcus
Accessions
- Primary accessionQ8DKE4
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000155914 | 1-407 | Ribonuclease Z | |||
Sequence: MEITFLGTSSGVPTRTRNVSSVALRLPQRKEIWLFDCGEATQHQLLRSDLRTSQIRRIFITHMHGDHIFGLMGLLASCGLAGTVSQIDVYGPPTLDRYIASCLRWSVMRLPYKLQVHTVEPGEVFSDGEFTVTCRLLHHRVPAFGYRVTEGDRPGRFHVEKAQALGIPFGPLYGQLKQGKTITLEDGRTFDGRDFCDPPQRGRSMVYCTDTVFCDSAVELAQQADVLIHEATFSHQEANLAFARLHSTSTMAAQVAAFAQVKLLFLTHFSARYAPGNPVQVEDLLAEAQAIFPNTRLAQDFLHYAIPRDGQICAEMPPSDSPAAANIDTLEATLEPLEAQTVAADAKNAPAIAINRATRQQMQQKLGIDATTANAILERRRQQKFTCLGELERLYPQVDWSALNVLF |
Interaction
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-308 | Ribonuclease Z | ||||
Sequence: MEITFLGTSSGVPTRTRNVSSVALRLPQRKEIWLFDCGEATQHQLLRSDLRTSQIRRIFITHMHGDHIFGLMGLLASCGLAGTVSQIDVYGPPTLDRYIASCLRWSVMRLPYKLQVHTVEPGEVFSDGEFTVTCRLLHHRVPAFGYRVTEGDRPGRFHVEKAQALGIPFGPLYGQLKQGKTITLEDGRTFDGRDFCDPPQRGRSMVYCTDTVFCDSAVELAQQADVLIHEATFSHQEANLAFARLHSTSTMAAQVAAFAQVKLLFLTHFSARYAPGNPVQVEDLLAEAQAIFPNTRLAQDFLHYAIPR | ||||||
Region | 309-407 | Unknown | ||||
Sequence: DGQICAEMPPSDSPAAANIDTLEATLEPLEAQTVAADAKNAPAIAINRATRQQMQQKLGIDATTANAILERRRQQKFTCLGELERLYPQVDWSALNVLF |
Sequence similarities
Belongs to the RNase Z family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length407
- Mass (Da)45,213
- Last updated2003-03-01 v1
- ChecksumC65FD56BA88A1601
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000039 EMBL· GenBank· DDBJ | BAC08467.1 EMBL· GenBank· DDBJ | Genomic DNA |