Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage.
Data detected yy1 yy2 and mbtps2 mRNA in primary mouse neurons microglia cells and astrocytes. In comparison to yy2 and mbtps2 yy1 revealed the highest expression level in all cell types.
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