Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex.Munz M., Bharioke A., Kosche G., Moreno-Juan V., Brignall A., Rodrigues T.M., Graff-Meyer A., Ulmer T., Haeuselmann S.[...], Roska B.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 95821PubMedEurope PMCCell 186:1930-1949.e31 (2023)Mapped to99+
BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation.Wischhof L., Lee H.M., Tutas J., Overkott C., Tedt E., Stork M., Peitz M., Brustle O., Ulas T.[...], Bano D.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCEMBO J 41:e110595-e110595 (2022)Mapped to52
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex.Sapir T., Kshirsagar A., Gorelik A., Olender T., Porat Z., Scheffer I.E., Goldstein D.B., Devinsky O., Reiner O.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCNat Commun 13:4209-4209 (2022)Mapped to99+
Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice.Longatti A., Ponzoni L., Moretto E., Giansante G., Lattuada N., Colombo M.N., Francolini M., Sala M., Murru L., Passafaro M.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCMol Neurobiol 58:6092-6110 (2021)Mapped to99+
Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon.Lin L., Zhang M., Stoilov P., Chen L., Zheng S.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCNeuron 107:1180-1196.e8 (2020)Mapped to51
<i>Ascl1</i> is required to specify a subset of ventromedial hypothalamic neurons.Aslanpour S., Rosin J.M., Balakrishnan A., Klenin N., Blot F., Gradwohl G., Schuurmans C., Kurrasch D.M.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCDevelopment 147:dev180067-dev180067 (2020)Mapped to62
The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc.Ambrozkiewicz M.C., Borisova E., Schwark M., Ripamonti S., Schaub T., Smorodchenko A., Weber A.I., Rhee H.J., Altas B.[...], Kawabe H.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCMol. Psychiatry 26:1980-1995 (2021)Cited in2Mapped to76
Prenatal expression of D-aspartate oxidase causes early cerebral D- aspartate depletion and influences brain morphology and cognitive functions at adulthood.De Rosa A., Mastrostefano F., Di Maio A., Nuzzo T., Saitoh Y., Katane M., Isidori A.M., Caputo V., Marotta P.[...], Errico F.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCAmino Acids 52:597-617 (2020)Cited in1Mapped to99+
The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability.Zeng F., Ma X., Zhu L., Xu Q., Zeng Y., Gao Y., Li G., Guo T., Zhang H.[...], Wang X.View abstractCategoriesFunction, ExpressionSourceMGI: 95821PubMedEurope PMCPLoS Biol 17:e3000525-e3000525 (2019)Mapped to99+
Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation.Giralt A., Brito V., Pardo M., Rubio S.E., Marion-Poll L., Martin-Ibanez R., Zamora-Moratalla A., Bosch C., Ballesteros J.J.[...], Canals J.M.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCExp Neurol 323:113095-113095 (2020)Mapped to99+
Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.Ma J., Zhang L.Q., He Z.X., He X.X., Wang Y.J., Jian Y.L., Wang X., Zhang B.B., Su C.[...], Zhu X.J.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCPLoS Biol. 17:e3000461-e3000461 (2019)Cited in3Mapped to99+
The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling.Zhang Z., Ye M., Li Q., You Y., Yu H., Ma Y., Mei L., Sun X., Wang L.[...], Zhang D.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCCell Rep 29:49-61.e7 (2019)Mapped to99+
Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation.Yang C.Y., Yu T.H., Wen W.L., Ling P., Hsu K.S.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCJ Neurosci 39:4959-4975 (2019)Mapped to99+
Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2<sup>-/-</sup> Mice.Chung C., Ha S., Kang H., Lee J., Um S.M., Yan H., Yoo Y.E., Yoo T., Jung H.[...], Kim E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95821PubMedEurope PMCBiol Psychiatry 85:534-543 (2019)Mapped to94
Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.Jung H., Park H., Choi Y., Kang H., Lee E., Kweon H., Roh J.D., Ellegood J., Choi W.[...], Kim E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95821PubMedEurope PMCNat Neurosci 21:1218-1228 (2018)Mapped to99+
SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function.Matt L., Kirk L.M., Chenaux G., Speca D.J., Puhger K.R., Pride M.C., Qneibi M., Haham T., Plambeck K.E.[...], Diaz E.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCCell Rep. 22:2246-2253 (2018)Cited in1Mapped to84
Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders.Nobili A., Krashia P., Cordella A., La Barbera L., Dell'Acqua M.C., Caruso A., Pignataro A., Marino R., Sciarra F.[...], D'Amelio M.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCMol Neurobiol 55:7921-7940 (2018)Mapped to68
IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2alpha.Tanabe Y., Naito Y., Vasuta C., Lee A.K., Soumounou Y., Linhoff M.W., Takahashi H.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCNat. Commun. 8:408-408 (2017)Cited in3Mapped to99+
Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice.Chen C.M., Orefice L.L., Chiu S.L., LeGates T.A., Hattar S., Huganir R.L., Zhao H., Xu B., Kuruvilla R.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCProc Natl Acad Sci U S A 114:E619-E628 (2017)Mapped to99+
Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation <i>In Vivo</i>.Chenaux G., Matt L., Hill T.C., Kaur I., Liu X.B., Kirk L.M., Speca D.J., McMahon S.A., Zito K.[...], Diaz E.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCeNeuro 3:ENEURO.0130-16.2016 (2016)Mapped to77
Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity.Liu K., Lei R., Li Q., Wang X.X., Wu Q., An P., Zhang J., Zhu M., Xu Z.[...], Li H.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCSci Rep 6:21019-21019 (2016)Mapped to99+
Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality.Huang T.N., Chuang H.C., Chou W.H., Chen C.Y., Wang H.F., Chou S.J., Hsueh Y.P.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCNat Neurosci 17:240-247 (2014)Mapped to99+
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.Koscielny G., Yaikhom G., Iyer V., Meehan T.F., Morgan H., Atienza-Herrero J., Blake A., Chen C.K., Easty R.[...], Parkinson H.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCNucleic Acids Res 42:D802-9 (2014)Mapped to99+
Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.Verpelli C., Dvoretskova E., Vicidomini C., Rossi F., Chiappalone M., Schoen M., Di Stefano B., Mantegazza R., Broccoli V.[...], Sala C.View abstractCategoryFunctionSourceMGI: 95821PubMedEurope PMCJ. Biol. Chem. 286:34839-34850 (2011)Cited in2Mapped to99+
A conditional knockout resource for the genome-wide study of mouse gene function.Skarnes W.C., Rosen B., West A.P., Koutsourakis M., Bushell W., Iyer V., Mujica A.O., Thomas M., Harrow J.[...], Bradley A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95821PubMedEurope PMCNature 474:337-342 (2011)Mapped to99+