Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.Lei Y., VanPortfliet J.J., Chen Y.F., Bryant J.D., Li Y., Fails D., Torres-Odio S., Ragan K.B., Deng J.[...], West A.P.View abstractAnnotationCooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.CategoriesFunction, InteractionSourceGeneRif: 214763, MGI: 2442261PubMedEurope PMCCell 186:3013-3032.e22 (2023)Mapped to47
MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation.Yang X., Shi C., Li H., Shen S., Su C., Yin H.View abstractAnnotationMARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation.CategoriesFunction, InteractionSourceGeneRif: 214763, MGI: 2442261PubMedEurope PMCSci. Signal. 15:eabk3067-eabk3067 (2022)Cited in3Mapped to15
TBK1 and IKKepsilon Act Redundantly to Mediate STING-Induced NF-kappaB Responses in Myeloid Cells.Balka K.R., Louis C., Saunders T.L., Smith A.M., Calleja D.J., D'Silva D.B., Moghaddas F., Tailler M., Lawlor K.E.[...], De Nardo D.View abstractCategoriesFunction, InteractionSourceMGI: 2442261PubMedEurope PMCCell Rep 31:107492-107492 (2020)Mapped to27
cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity.Liu H., Moura-Alves P., Pei G., Mollenkopf H.J., Hurwitz R., Wu X., Wang F., Liu S., Ma M.[...], Kaufmann S.H.View abstractCategoriesFunction, Interaction, Subcellular LocationSourceMGI: 2442261PubMedEurope PMCEMBO Rep 20:e46293-e46293 (2019)Mapped to15
ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response.Lian H., Wei J., Zang R., Ye W., Yang Q., Zhang X.N., Chen Y.D., Fu Y.Z., Hu M.M.[...], Shu H.B.View abstractAnnotationZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune responseCategoriesFunction, InteractionSourceGeneRif: 214763, MGI: 2442261PubMedEurope PMCNat. Commun. 9:3349-3349 (2018)Cited in3Mapped to6
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.Orzalli M.H., Broekema N.M., Diner B.A., Hancks D.C., Elde N.C., Cristea I.M., Knipe D.M.View abstractAnnotationIFI16 and cGAS cooperate in a novel way to sense nuclear herpesviral DNA and initiate innate signalingCategoriesInteractionSourceGeneRif: 214763PubMedEurope PMCProc Natl Acad Sci U S A 112:E1773-81 (2015)Mapped to9