Q8C3M7 · Q8C3M7_MOUSE

  • Protein
    Guanine nucleotide-binding protein subunit alpha
  • Gene
    Gna14
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

function

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Features

Showing features for binding site.

135550100150200250300350
TypeIDPosition(s)Description
Binding site45-50GTP (UniProtKB | ChEBI)
Binding site49Mg2+ (UniProtKB | ChEBI)
Binding site151-152GTP (UniProtKB | ChEBI)
Binding site176-182GTP (UniProtKB | ChEBI)
Binding site182Mg2+ (UniProtKB | ChEBI)
Binding site201-205GTP (UniProtKB | ChEBI)
Binding site270-273GTP (UniProtKB | ChEBI)
Binding site327GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentheterotrimeric G-protein complex
Molecular FunctionG protein-coupled receptor binding
Molecular FunctionG-protein beta/gamma-subunit complex binding
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmetal ion binding
Biological ProcessG protein-coupled receptor signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Guanine nucleotide-binding protein subunit alpha

Gene names

    • Name
      Gna14

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q8C3M7

Organism-specific databases

Subcellular Location

PTM/Processing

Proteomic databases

Interaction

Subunit

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

Family & Domains

Sequence similarities

Belongs to the G-alpha family. G(q) subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    355
  • Mass (Da)
    41,469
  • Last updated
    2003-03-01 v1
  • MD5 Checksum
    C9C8FF945AC57F6F35A35A328A173251
MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYMCEQNKENAQIIREVEVDKVTALSRDQVAAIKQLWLDPGIQECYDRRREYQLSDSAKYYLTDIERIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFRTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIPFVFAAVKDTILQLNLREFNLV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK085444
EMBL· GenBank· DDBJ
BAC39447.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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