Q8C3M7 · Q8C3M7_MOUSE
- ProteinGuanine nucleotide-binding protein subunit alpha
- GeneGna14
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids355 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 45-50 | GTP (UniProtKB | ChEBI) | |||
Binding site | 49 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 151-152 | GTP (UniProtKB | ChEBI) | |||
Binding site | 176-182 | GTP (UniProtKB | ChEBI) | |||
Binding site | 182 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 201-205 | GTP (UniProtKB | ChEBI) | |||
Binding site | 270-273 | GTP (UniProtKB | ChEBI) | |||
Binding site | 327 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | heterotrimeric G-protein complex | |
Molecular Function | G protein-coupled receptor binding | |
Molecular Function | G-protein beta/gamma-subunit complex binding | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | metal ion binding | |
Biological Process | G protein-coupled receptor signaling pathway |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameGuanine nucleotide-binding protein subunit alpha
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ8C3M7
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Interaction
Subunit
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Structure
Sequence
- Sequence statusComplete
- Length355
- Mass (Da)41,469
- Last updated2003-03-01 v1
- MD5 ChecksumC9C8FF945AC57F6F35A35A328A173251
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK085444 EMBL· GenBank· DDBJ | BAC39447.1 EMBL· GenBank· DDBJ | mRNA |