Q8C0X4 · Q8C0X4_MOUSE
- ProteinCentromere protein Cenp-F N-terminal domain-containing protein
- GeneCenpf
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids952 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | axoneme | |
Cellular Component | centrosome | |
Cellular Component | chromosome, centromeric region | |
Cellular Component | ciliary basal body | |
Cellular Component | ciliary transition fiber | |
Cellular Component | nucleus | |
Cellular Component | pronucleus | |
Cellular Component | spindle pole | |
Molecular Function | dynein complex binding | |
Molecular Function | microtubule binding | |
Biological Process | metaphase chromosome alignment | |
Biological Process | mitotic cell cycle | |
Biological Process | regulation of G2/M transition of mitotic cell cycle | |
Biological Process | regulation of striated muscle tissue development |
Names & Taxonomy
Protein names
- Recommended nameCentromere protein Cenp-F N-terminal domain-containing protein
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ8C0X4
Organism-specific databases
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain, coiled coil, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-288 | Centromere protein Cenp-F N-terminal | ||||
Sequence: MSWALEEWKEGLPSRALQKIQELEGQLEKLKKEKQQRQFQLDSLEAALQKQKQKVEDGKTEGADLKRENQRLMEICEHLEKSRQKLSHELQVKESQVNLQESQLSSCKKQIEKLEQELKRCKSEFERSQQVAQSADVSLNPCSTPQKLFATPLTPSSTYEDLKEKYNKEVEERKRLEEEVKALHAKKVSLPFSQATMNHRDIARHQASSSVFPWQQENTPSRLSSDALKTPLRRDGSAAHFLGEEVSPNKSSMKTGRGDCSSLPDLKSKMTELELRLQGQEKEMRSQV | ||||||
Coiled coil | 13-131 | |||||
Sequence: PSRALQKIQELEGQLEKLKKEKQQRQFQLDSLEAALQKQKQKVEDGKTEGADLKRENQRLMEICEHLEKSRQKLSHELQVKESQVNLQESQLSSCKKQIEKLEQELKRCKSEFERSQQV | ||||||
Coiled coil | 159-186 | |||||
Sequence: YEDLKEKYNKEVEERKRLEEEVKALHAK | ||||||
Coiled coil | 263-378 | |||||
Sequence: LPDLKSKMTELELRLQGQEKEMRSQVNKCQDLQVQLEKTKVELIEKERILNKTRDEVVRSTAQYDQAAAKCTTLEQKLKTLTEELSCHRQNAESAKRSLEQRIKEKEKELQEELSR | ||||||
Region | 445-473 | Disordered | ||||
Sequence: ASQVAENELRRSSEEMKKENSLIRSQSEQ | ||||||
Compositional bias | 452-473 | Basic and acidic residues | ||||
Sequence: ELRRSSEEMKKENSLIRSQSEQ | ||||||
Coiled coil | 499-660 | |||||
Sequence: AEEMKAKNTSQEIMLRDLQEKLNQQENSLTLEKLKLALADLERQRNCSQVLLKKREHHIDQLNNKLNKIEKEFETLLSALELKKKECEELKEEKNQISFWKIDSEKLINQIESEKEILLGKINHLETSLKTQQVSPDSNERIRTLEMERENFTVEIKNLQSM | ||||||
Coiled coil | 693-720 | |||||
Sequence: IENMCLKANKLTGQVESLECKLQLLSSE | ||||||
Region | 746-780 | Disordered | ||||
Sequence: GSSLVTNEDNQRSSEDNQRSSEDNQRGSLAFEQQP | ||||||
Coiled coil | 814-862 | |||||
Sequence: IAILQNRVTSLESSLESQNQMNSDLQMRCEELLQIKGEVEENLSKAEQI | ||||||
Coiled coil | 888-922 | |||||
Sequence: VAETLATLESKEKELQLLKEKLEAQQTEVQKLNKN |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length952
- Mass (Da)110,038
- Last updated2003-03-01 v1
- Checksum23E80B0F8D565BA8
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 452-473 | Basic and acidic residues | ||||
Sequence: ELRRSSEEMKKENSLIRSQSEQ | ||||||
Non-terminal residue | 952 | |||||
Sequence: S |