Q8BYR8 · S41A2_MOUSE

  • Protein
    Solute carrier family 41 member 2
  • Gene
    Slc41a2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

function

Acts as a plasma-membrane magnesium transporter (PubMed:15809054).
Can also mediate the transport of other divalent metal cations in an order of Ba2+ > Ni2+ > Co2+ > Fe2+ > Mn2+ (PubMed:15809054).

Catalytic activity

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
0.34 mMMg2+

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioninorganic cation transmembrane transporter activity
Molecular Functionmonoatomic cation transmembrane transporter activity
Biological Processcobalt ion transport
Biological Processiron ion transport
Biological Processmagnesium ion transport
Biological Processmanganese ion transport
Biological Processmetal ion transport
Biological Processnickel cation transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Solute carrier family 41 member 2

Gene names

    • Name
      Slc41a2

Organism names

  • Taxonomic identifier
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q8BYR8

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-162Extracellular
Transmembrane163-183Helical
Topological domain184-195Cytoplasmic
Transmembrane196-216Helical
Topological domain217-245Extracellular
Transmembrane246-266Helical
Topological domain267-282Cytoplasmic
Transmembrane283-303Helical
Topological domain304-313Extracellular
Transmembrane314-334Helical
Topological domain335-347Cytoplasmic
Transmembrane348-368Helical
Topological domain369-376Extracellular
Transmembrane377-397Helical
Topological domain398-406Cytoplasmic
Transmembrane407-427Helical
Topological domain428-469Extracellular
Transmembrane470-490Helical
Topological domain491-498Cytoplasmic
Transmembrane499-519Helical
Topological domain520-543Extracellular
Transmembrane544-564Helical
Topological domain565-573Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, modified residue (large scale data), modified residue.

Type
IDPosition(s)Source
Description
ChainPRO_00002950421-573UniProtSolute carrier family 41 member 2
Modified residue (large scale data)113PTMeXchangePhosphotyrosine
Modified residue (large scale data)116PTMeXchangePhosphotyrosine
Modified residue (large scale data)118PTMeXchangePhosphotyrosine
Modified residue137UniProtPhosphoserine
Modified residue (large scale data)137PTMeXchangePhosphoserine
Modified residue138UniProtPhosphoserine
Modified residue (large scale data)138PTMeXchangePhosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Family & Domains

Sequence similarities

Belongs to the SLC41A transporter family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    573
  • Mass (Da)
    62,305
  • Last updated
    2003-03-01 v1
  • MD5 Checksum
    54CD74794F96BC59EF1517DDCD5C3E89
MTHSKGRPVTYKTSASPESGGGFVDWTLNLNTIQSDKFLNLLLSMVPVIYQKNQEDRHKKVNGIWQDGLSGAAQTFSKRSEPHLDYHEFSEQAFHSSSSGHTPASCSPKYDDYAGYNYCDGREASETTAMLQDEDLSSEGDDVIVETSQRIPKESSGVMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFKNVTEVFILVPALLGLKGNLEMTLASRLSTAVNVGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLSHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVCAFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPEEPKGCSYPFRTFFGSGVNNKSAQVLLLFVIPGHLIFLYTIHLMKSGHTSLTVVFVVVYLFAAVLQVFTLLWIADWMVHRFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
D3YYW2D3YYW2_MOUSESlc41a212
D3Z5A5D3Z5A5_MOUSESlc41a2131
D3YWW0D3YWW0_MOUSESlc41a289

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK038549
EMBL· GenBank· DDBJ
BAC30038.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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