Q8BYC4 · GPR20_MOUSE
- ProteinG-protein coupled receptor 20
- GeneGpr20
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids358 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | plasma membrane | |
Cellular Component | receptor complex | |
Molecular Function | G protein-coupled receptor activity | |
Biological Process | phospholipase C-activating G protein-coupled receptor signaling pathway | |
Biological Process | positive regulation of Rho protein signal transduction |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameG-protein coupled receptor 20
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ8BYC4
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-46 | Extracellular | ||||
Sequence: MPSALSMRPWDAALPNTTAAAWTNGSVPEMPLFHHFARLDEELQAT | ||||||
Transmembrane | 47-67 | Helical; Name=1 | ||||
Sequence: FPSLWQALMVVHGTIFLAGLV | ||||||
Topological domain | 68-84 | Cytoplasmic | ||||
Sequence: LNGLALYVFCCRTRAKT | ||||||
Transmembrane | 85-105 | Helical; Name=2 | ||||
Sequence: PSVTYTINLVVTDLLVGLSLP | ||||||
Topological domain | 106-123 | Extracellular | ||||
Sequence: TRFAVFYGARGCLRCAFP | ||||||
Transmembrane | 124-144 | Helical; Name=3 | ||||
Sequence: HVLGYFLNMHCSILFLTCICV | ||||||
Topological domain | 145-166 | Cytoplasmic | ||||
Sequence: DRYLAIVQPEGSRRWRQPACAK | ||||||
Transmembrane | 167-188 | Helical; Name=4 | ||||
Sequence: AVCIFVWLAAGVVTLSVLGVKS | ||||||
Topological domain | 189-195 | Extracellular | ||||
Sequence: GGRSCCR | ||||||
Transmembrane | 196-216 | Helical; Name=5 | ||||
Sequence: VFALTVLEFLLPLLVISVFTG | ||||||
Topological domain | 217-237 | Cytoplasmic | ||||
Sequence: RIMCALSRPGLLRQGRQRRVR | ||||||
Transmembrane | 238-258 | Helical; Name=6 | ||||
Sequence: AMQLLLTVLVIFLVCFTPFHA | ||||||
Topological domain | 259-274 | Extracellular | ||||
Sequence: RQVAVALWPNVPKHTS | ||||||
Transmembrane | 275-295 | Helical; Name=7 | ||||
Sequence: LVAYHVAVTLSSLNSCMDPIV | ||||||
Topological domain | 296-358 | Cytoplasmic | ||||
Sequence: YCFITSGFQATVRGLFYQRGEEFKPSSMDVVSMHKSTKASAPIHILSIGSHTLTQPLTNGPEP |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000303233 | 1-358 | G-protein coupled receptor 20 | |||
Sequence: MPSALSMRPWDAALPNTTAAAWTNGSVPEMPLFHHFARLDEELQATFPSLWQALMVVHGTIFLAGLVLNGLALYVFCCRTRAKTPSVTYTINLVVTDLLVGLSLPTRFAVFYGARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVQPEGSRRWRQPACAKAVCIFVWLAAGVVTLSVLGVKSGGRSCCRVFALTVLEFLLPLLVISVFTGRIMCALSRPGLLRQGRQRRVRAMQLLLTVLVIFLVCFTPFHARQVAVALWPNVPKHTSLVAYHVAVTLSSLNSCMDPIVYCFITSGFQATVRGLFYQRGEEFKPSSMDVVSMHKSTKASAPIHILSIGSHTLTQPLTNGPEP | ||||||
Glycosylation | 16 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 24 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Ubiquitous expressed with abundant expression in intestinal tissues.
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length358
- Mass (Da)39,432
- Last updated2003-03-01 v1
- ChecksumC6F7842ABDE9CA8F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC117783 EMBL· GenBank· DDBJ | AAI17784.1 EMBL· GenBank· DDBJ | mRNA | ||
AK040547 EMBL· GenBank· DDBJ | BAC30623.1 EMBL· GenBank· DDBJ | mRNA | ||
AY255575 EMBL· GenBank· DDBJ | AAO85087.1 EMBL· GenBank· DDBJ | mRNA |