Q8BXJ8 · Z385B_MOUSE

  • Protein
    Zinc finger protein 385B
  • Gene
    Znf385b
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

May play a role in p53/TP53-mediated apoptosis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular Functionnucleic acid binding
Molecular Functionzinc ion binding
Biological Processintrinsic apoptotic signaling pathway by p53 class mediator

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Zinc finger protein 385B
  • Alternative names
    • Zinc finger protein 533

Gene names

    • Name
      Znf385b
    • Synonyms
      Zfp385b, Zfp533, Znf533

Organism names

  • Taxonomic identifier
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q8BXJ8
  • Secondary accessions
    • Q8BWQ7

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001918131-482Zinc finger protein 385B

Proteomic databases

PTM databases

Expression

Developmental stage

Mainly expressed in developing brain.

Gene expression databases

Interaction

Subunit

Interacts with p53/TP53; the interaction is direct.

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for region, zinc finger, compositional bias.

TypeIDPosition(s)Description
Region1-105Required for induction of apoptosis
Zinc finger34-64Matrin-type 1
Region54-75Disordered
Region106-482Interaction with p53/TP53
Zinc finger169-199Matrin-type 2
Compositional bias189-211Basic and acidic residues
Region189-259Disordered
Compositional bias242-259Polar residues
Compositional bias268-284Polar residues
Region268-287Disordered
Zinc finger294-328Matrin-type 3
Region331-352Disordered
Zinc finger360-390Matrin-type 4
Region378-397Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q8BXJ8-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    482
  • Mass (Da)
    51,356
  • Last updated
    2003-03-01 v1
  • Checksum
    C9F234F5E18E1B71
MNMATFLRGFEEKGLKNDRPGDQFSKEKKKILFSFCEVCNIQLNSAAQAQVHYDGKSHRKRVKQLSDGQPPPPVQGSVPLLAGPCPCPGPGPNTSTGSACHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKMVPSKDSAKANPSCSIRPGTGDSSDKSEDKGKIKATSSSQPSGSEGGSFLLKSGTTPLPLGAIASPSKSTNGAPGSVAESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNGSKGSGLQNKMFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDLMKPLAPTFLSSPLAAAAVSSALSLPPRPSASLFQAAAIPPALLRPGHGPIRATPASILFAPY

Q8BXJ8-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
G5E8Y8G5E8Y8_MOUSEZfp385b394
Q8BM98Q8BM98_MOUSEZfp385b111

Features

Showing features for alternative sequence, compositional bias.

TypeIDPosition(s)Description
Alternative sequenceVSP_0159811-114in isoform 2
Compositional bias189-211Basic and acidic residues
Compositional bias242-259Polar residues
Compositional bias268-284Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK046798
EMBL· GenBank· DDBJ
BAC32874.1
EMBL· GenBank· DDBJ
mRNA
AK050293
EMBL· GenBank· DDBJ
BAC34170.1
EMBL· GenBank· DDBJ
mRNA
AK149352
EMBL· GenBank· DDBJ
BAE28828.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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