Q8BWD2 · IP6K3_MOUSE

  • Protein
    Inositol hexakisphosphate kinase 3
  • Gene
    Ip6k3
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 (By similarity).

Catalytic activity

Features

Showing features for binding site.

139650100150200250300350
TypeIDPosition(s)Description
Binding site206-214substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functioninositol hexakisphosphate 1-kinase activity
Molecular Functioninositol hexakisphosphate 3-kinase activity
Molecular Functioninositol hexakisphosphate 5-kinase activity
Molecular Functioninositol hexakisphosphate 6-kinase activity
Molecular Functioninositol hexakisphosphate kinase activity
Molecular Functioninositol-1,3,4,5,6-pentakisphosphate kinase activity
Biological Processinositol phosphate biosynthetic process
Biological Processlocomotion
Biological Processphosphatidylinositol phosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inositol hexakisphosphate kinase 3
  • EC number
  • Short names
    InsP6 kinase 3
  • Alternative names
    • Inositol hexaphosphate kinase 3

Gene names

    • Name
      Ip6k3
    • Synonyms
      Ihpk3

Organism names

  • Taxonomic identifier
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q8BWD2

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000668821-396Inositol hexakisphosphate kinase 3

Proteomic databases

PTM databases

Expression

Tissue specificity

Highly expressed in cerebellum, brain cortex, kidney, thymus and lung. Detected at lower levels in hippocampus, testis, heart and olfactory bulb.

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    396
  • Mass (Da)
    44,418
  • Last updated
    2003-03-01 v1
  • Checksum
    DB98CB79B4B36EE0
MVVRHSSDKGKIGVGVPLEPFLHQVGGHLSVLQYDAYTVCKPLVSQEQKFYESLPLAMKCFTPKYKGTITVRLRRDSRGHLGLVANPLKENLEPFQVSPESRAVALWQTLQQTTGSESSPCPLTQLARSLKESAAKVLLRSDCHLSTQASPLVESEDGSQVERKGFNPWGLHCHQAHLTRLCSQYPEDKRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKARHMKKCAQSTSACLGVRICGMQVYQTDQKSFLCKDKYYGRKLSVEGFRQALSQFLHDGTRLRAELLEPILRRLQALLTVIRSQSSYRFYSSSVLIIYDGEPPQTTQGSTSGGVTSGDPAKVDVRMIDFAHTTFKGSWNEHTTYEGPDPGYIFGLENLIGILRDIQEGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK052857
EMBL· GenBank· DDBJ
BAC35176.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp