Q8BWD2 · IP6K3_MOUSE
- ProteinInositol hexakisphosphate kinase 3
- GeneIp6k3
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids396 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 (By similarity).
Catalytic activity
- 1D-myo-inositol hexakisphosphate + ATP = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 206-214 | substrate | ||||
Sequence: PCILDLKMG |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | inositol hexakisphosphate 1-kinase activity | |
Molecular Function | inositol hexakisphosphate 3-kinase activity | |
Molecular Function | inositol hexakisphosphate 5-kinase activity | |
Molecular Function | inositol hexakisphosphate 6-kinase activity | |
Molecular Function | inositol hexakisphosphate kinase activity | |
Molecular Function | inositol-1,3,4,5,6-pentakisphosphate kinase activity | |
Biological Process | inositol phosphate biosynthetic process | |
Biological Process | locomotion | |
Biological Process | phosphatidylinositol phosphate biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameInositol hexakisphosphate kinase 3
- EC number
- Short namesInsP6 kinase 3
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ8BWD2
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000066882 | 1-396 | Inositol hexakisphosphate kinase 3 | |||
Sequence: MVVRHSSDKGKIGVGVPLEPFLHQVGGHLSVLQYDAYTVCKPLVSQEQKFYESLPLAMKCFTPKYKGTITVRLRRDSRGHLGLVANPLKENLEPFQVSPESRAVALWQTLQQTTGSESSPCPLTQLARSLKESAAKVLLRSDCHLSTQASPLVESEDGSQVERKGFNPWGLHCHQAHLTRLCSQYPEDKRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKARHMKKCAQSTSACLGVRICGMQVYQTDQKSFLCKDKYYGRKLSVEGFRQALSQFLHDGTRLRAELLEPILRRLQALLTVIRSQSSYRFYSSSVLIIYDGEPPQTTQGSTSGGVTSGDPAKVDVRMIDFAHTTFKGSWNEHTTYEGPDPGYIFGLENLIGILRDIQEGE |
Proteomic databases
PTM databases
Expression
Tissue specificity
Highly expressed in cerebellum, brain cortex, kidney, thymus and lung. Detected at lower levels in hippocampus, testis, heart and olfactory bulb.
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length396
- Mass (Da)44,418
- Last updated2003-03-01 v1
- ChecksumDB98CB79B4B36EE0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK052857 EMBL· GenBank· DDBJ | BAC35176.1 EMBL· GenBank· DDBJ | mRNA |