Q8BQ93 · Q8BQ93_MOUSE

  • Protein
    Aldehyde dehydrogenase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

Catalytic activity

  • (2E)-hexadecenal + NAD+ + H2O = (E)-hexadec-2-enoate + NADH + 2 H+
  • (2E,6E)-farnesal + NAD+ + H2O = (2E,6E)-farnesoate + NADH + 2 H+
    EC:1.2.1.94 (UniProtKB | ENZYME | Rhea)
  • hexadecanoate + NADH + 2 H+ = hexadecanal + NAD+ + H2O
  • 2,6,10,14-tetramethylpentadecanal + NAD+ + H2O = 2,6,10,14-tetramethylpentadecanoate + NADH + 2 H+
  • 22-oxodocosanoate + NAD+ + H2O = docosanedioate + NADH + 2 H+
  • octadecanal + NAD+ + H2O = octadecanoate + NADH + 2 H+
  • octanal + NAD+ + H2O = octanoate + NADH + 2 H+
  • tetradecanal + NAD+ + H2O = tetradecanoate + NADH + 2 H+
  • heptanal + NAD+ + H2O = heptanoate + NADH + 2 H+
  • a fatty aldehyde + NAD+ + H2O = a fatty acid + NADH + 2 H+
  • an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+
    EC:1.2.1.3 (UniProtKB | ENZYME | Rhea)
  • decanal + NAD+ + H2O = decanoate + NADH + 2 H+
  • dodecanoate + NADH + 2 H+ = dodecanal + NAD+ + H2O

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site207
Active site241

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionaldehyde dehydrogenase (NAD+) activity
Biological Processcellular aldehyde metabolic process
Biological Processfatty acid metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Aldehyde dehydrogenase

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q8BQ93

Subcellular Location

Endoplasmic reticulum membrane
; Single-pass membrane protein
Microsome membrane

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane464-484Helical

Keywords

PTM/Processing

Proteomic databases

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-421Aldehyde dehydrogenase

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    487
  • Mass (Da)
    54,300
  • Last updated
    2003-03-01 v1
  • Checksum
    BF0EE346B26FF6C1
MERQVLRLRQAFRSGRSRPLRFRLQQLEALRRMVQEREKEILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKNLLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTMQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQYLDQDLYAIVNGGIPETTELLKQRFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDRDCDLDVACRRIAWGKYMNCGQACIAPDYILCEASLQNQIVQKIKETVKDFYGENIKASPDYERIINLRHFKRLQSLLKGQKIAFGGEMDEATRYLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAINFINDREKPLALYVFSRNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLKGESVNKLRYPPNSESKVSWAKFFLLKQFNKGRLGMLLFVCLVAVAAVIVKFVLERA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK051219
EMBL· GenBank· DDBJ
BAC34563.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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