Q8BQ30 · PPR18_MOUSE

  • Protein
    Phostensin
  • Gene
    Ppp1r18
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

May target protein phosphatase 1 to F-actin cytoskeleton.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytoskeleton
Molecular Functionactin binding
Molecular Functionphosphatase binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Phostensin
  • Alternative names
    • Protein phosphatase 1 F-actin cytoskeleton-targeting subunit
    • Protein phosphatase 1 regulatory subunit 18

Gene names

    • Name
      Ppp1r18

Organism names

  • Taxonomic identifier
  • Strains
    • C57BL/6J
    • FVB/N
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q8BQ30
  • Secondary accessions
    • B8JJ63
    • B8JJ64
    • Q3UDS6
    • Q8CEY9
    • Q8R3D8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00000508091-594Phostensin
Modified residue126Phosphoserine
Modified residue134Phosphoserine
Modified residue174Phosphoserine
Modified residue194Phosphoserine
Modified residue198Phosphothreonine
Modified residue224Phosphoserine
Modified residue412Phosphoserine
Modified residue437N6-acetyllysine
Modified residue510Phosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Interacts with Protein phosphatase 1 (PP1).

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias18-52Basic and acidic residues
Region18-238Disordered
Compositional bias89-109Polar residues
Compositional bias134-156Basic and acidic residues
Compositional bias207-221Basic and acidic residues
Compositional bias294-323Polar residues
Region294-485Disordered
Compositional bias403-422Pro residues
Region531-577Disordered
Compositional bias557-572Acidic residues

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q8BQ30-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    594
  • Mass (Da)
    65,630
  • Last updated
    2003-03-01 v1
  • Checksum
    6B7B10B39C5B44BA
MTAIPDWKLQLLARRRQEEAAVRGREKAERDRLSQMPAWKRGILERRRAKLGLPPGEGSPVPGNAEAGPPDPDESAVLLEAIGPVHQNRFIQQERQRQQQQQQQQRNEVLGDRKAGPLEVLERRSSPGNLRDQSPKGRESREERLSPRESRDRRLVIGGAQESSSRSLRDWRQSPAEARDLSSRPAEAQKWRLSPGETPEESLRLAGSGDDSPKRKEVLESILSPGEPGDQKASPTDVHKWNLDSREPQKQSLIQLEATEWRLKSGEERKDYLEGCGREEEKLSSGIVPVTKEVQDITSSEVETAEQRPTESWKWTLNSGKARERTTWDIDTQTQKPDPPASSEKHPGPSGMEAEEEAEKEEAEAQSRPLRAQQNLCSGPSPLPPEHSGTEGSRQQEEEAAEPRPPTPAPLSPPPSAPTAPQPSGDPLMSRLFYGVKPGPGVGAPRRSGHTFTVNPRRCAPPASPAPPVNPATADAAGSGSGKKRYPTAEEILVLGGYLRLSRSCLVKGSPERHHKQLKISFSETALETTYQYPSESSVLEDLGPEPETPIAPLATQPDEEEEEEEEEEELLLQPGLQGGLRTKALIVDESCRR

Q8BQ30-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical
    • 589-594: DESCRR → GKRLRPGWRRAPPGVCGVVVL

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A087WRI9A0A087WRI9_MOUSEPpp1r18166

Sequence caution

The sequence AAH25573.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.

Features

Showing features for compositional bias, sequence conflict, alternative sequence.

TypeIDPosition(s)Description
Compositional bias18-52Basic and acidic residues
Compositional bias89-109Polar residues
Compositional bias134-156Basic and acidic residues
Compositional bias207-221Basic and acidic residues
Sequence conflict278in Ref. 3; AAH25573
Compositional bias294-323Polar residues
Compositional bias403-422Pro residues
Compositional bias557-572Acidic residues
Alternative sequenceVSP_014260589-594in isoform 2

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK009340
EMBL· GenBank· DDBJ
BAC25252.1
EMBL· GenBank· DDBJ
mRNA
AK051656
EMBL· GenBank· DDBJ
BAC34706.1
EMBL· GenBank· DDBJ
mRNA
AK149943
EMBL· GenBank· DDBJ
BAE29185.1
EMBL· GenBank· DDBJ
mRNA
CR974451
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BC025573
EMBL· GenBank· DDBJ
AAH25573.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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