Q8BIV7 · S45A1_MOUSE
- ProteinProton-associated sugar transporter A
- GeneSlc45a1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids751 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Proton-associated glucose transporter in the brain.
Catalytic activity
- D-galactose(in) + H+(in) = D-galactose(out) + H+(out)D-galactose (in)CHEBI:4139
+ H+ (in)CHEBI:15378= D-galactose (out)CHEBI:4139+ H+ (out)CHEBI:15378 - D-glucose(out) + H+(out) = D-glucose(in) + H+(in)
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | galactose:proton symporter activity | |
Molecular Function | glucose transmembrane transporter activity | |
Molecular Function | glucose:proton symporter activity | |
Molecular Function | sucrose:proton symporter activity | |
Biological Process | galactose transmembrane transport | |
Biological Process | glucose transmembrane transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameProton-associated sugar transporter A
- Short namesPAST-A
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ8BIV7
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 93-113 | Helical | ||||
Sequence: ILFGIEFSYAMETAYVTPVLL | ||||||
Transmembrane | 123-143 | Helical | ||||
Sequence: SLVWFISPILGFLLQPLLGAW | ||||||
Transmembrane | 155-175 | Helical | ||||
Sequence: RPFILVLAIGALLGLSLLLNG | ||||||
Transmembrane | 191-211 | Helical | ||||
Sequence: WGILLTVCGVVLMDFSADSAD | ||||||
Transmembrane | 233-253 | Helical | ||||
Sequence: IHALMAGLGGGFGYVVGGIHW | ||||||
Transmembrane | 268-288 | Helical | ||||
Sequence: VIYVFTAITLSVTTVLTLISI | ||||||
Transmembrane | 536-556 | Helical | ||||
Sequence: GWLSFEGMLLFYTDFMGEVVF | ||||||
Transmembrane | 576-596 | Helical | ||||
Sequence: VTMGCWGMCIYAFSAAFYSAI | ||||||
Transmembrane | 606-626 | Helical | ||||
Sequence: VRTLYFIAYLAFGLGTGLATL | ||||||
Transmembrane | 630-650 | Helical | ||||
Sequence: LYVVLSLCTTYGILFSTLCTL | ||||||
Transmembrane | 688-708 | Helical | ||||
Sequence: FLAQILVSLVLGPLTSAVGSA | ||||||
Transmembrane | 710-730 | Helical | ||||
Sequence: GVMYFSSLVSFLGCLYSSLCV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000122515 | 1-751 | Proton-associated sugar transporter A | |||
Sequence: MIPPASSTPPGEAVIPSVAPQDFWRSPISSYSGSVTGHISHRANNFKRHPKRRKYIRPSPPPPPNTPCPIELVDFGDLHPQRSFWELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALADTATNHKWGILLTVCGVVLMDFSADSADNPSHAYMMDVCGPVDQDRGLNIHALMAGLGGGFGYVVGGIHWDKTSFGRALGGQLRVIYVFTAITLSVTTVLTLISIPERPLRPLGEKRTAMKSPSLPLPPSPPVLLEEGAGDALPSTTATSLYASFSSPISPPSPLTPKYGSFISRDSSLTGINEFASSFGTSNIDSVLIDCFTAGHDNYLALPSSVPRQAISVSFPRAPDGFYCQERGLERREGPLTLGSDGDVLRVGSLDTSKPRASGILKRPQTLALPDVAGGNGPETSRRRNVTFSQQVANILLNGVKYESELTGSSEQSEQPLSLRHLCSTIYNMPKALRNLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEECLSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLCVTYEIPSVDAADEERQPLLLNV | ||||||
Modified residue | 500 | Phosphothreonine | ||||
Sequence: T |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length751
- Mass (Da)81,474
- Last updated2006-05-16 v3
- Checksum129F390E154F6BBD
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
B0QZL3 | B0QZL3_MOUSE | Slc45a1 | 675 |
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 287 | in Ref. 1; BAE34311 | ||||
Sequence: S → R | ||||||
Sequence conflict | 433 | in Ref. 1; BAE34311 | ||||
Sequence: S → L |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK082651 EMBL· GenBank· DDBJ | - | mRNA | No translation available. | |
AK158002 EMBL· GenBank· DDBJ | BAE34311.1 EMBL· GenBank· DDBJ | mRNA |