Q8BI71 · EX3L1_MOUSE
- ProteinExocyst complex component 3-like protein
- GeneExoc3l1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids739 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
As part of the exocyst, may play a role in regulated exocytosis of insulin granules.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | exocyst | |
Cellular Component | secretory granule | |
Cellular Component | transport vesicle | |
Molecular Function | SNARE binding | |
Biological Process | exocyst localization | |
Biological Process | exocytosis | |
Biological Process | peptide hormone secretion |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameExocyst complex component 3-like protein
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ8BI71
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Colocalizes with insulin granules.
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000309475 | 1-739 | Exocyst complex component 3-like protein | |||
Sequence: MDSKIQPTLRPGSSCPRPEWPEQERAEQLARGAALKWASGIFYRPEQLTRLGQYRSREIQRNYSLEARIKSVVQSYLEGVQTGVWQLTRALEAVQGTREALSQAHHLLKGLSRTSQTLEPLRECVVQHKQLQILTRLLPRLQAVPATVAHTQTLIDSERLLEAYVSLRELEQLKEETLAPLGGLELPIFQGLGLLAEALGQAVEAAAGAAGRLAREDPALLVAAIRVAEVETERTILGQAPRDWRQRCLRALQEGLERVHFASPVLPEPGALAGWLEALQVALPAELATAEALVAPCCPPSYRVVELWAHTLHSGLRRSVQQLLAGPELGAADTFALLHWALHVYTGKEMMGNLELGPEADVSQLEPLLTSENIEQLEAAFVAQVQVSVAQWLKKALDGEVAEWSGEQEPPTDPSGFYHSPMPAIVLQILAENIQVTNLISDSLHRRAHNMAVSELGAFLRSFSDALIRFSRDHLRGDAVAPHYVPYLLSAFNHQSALRSSVSVLLPDGEASGVLAPVEAALDDVQRRICRLVLEVLQVELQPLFSALPSRRWLLSSELLDGVCEQTSHFCQDFWRVRKPGVQLLLAEAERTVVLQYLRALMQGRLVCRGTDERSQAAERLRQDAAQLKELFLGLGLEESAHCAPVLLALRELLNLHDPTLLGLEVAGLRQQFPDVSEDHVSALLDLRGDVSREHRQAALSSLQAGPPPSPSTGRRALFSLVPTPTPSLSSCLPSGPCS |
Proteomic databases
PTM databases
Expression
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-21 | Disordered | ||||
Sequence: MDSKIQPTLRPGSSCPRPEWP | ||||||
Region | 1-370 | Mediates interaction with EXOC2, EXOC4 and EXOC5 | ||||
Sequence: MDSKIQPTLRPGSSCPRPEWPEQERAEQLARGAALKWASGIFYRPEQLTRLGQYRSREIQRNYSLEARIKSVVQSYLEGVQTGVWQLTRALEAVQGTREALSQAHHLLKGLSRTSQTLEPLRECVVQHKQLQILTRLLPRLQAVPATVAHTQTLIDSERLLEAYVSLRELEQLKEETLAPLGGLELPIFQGLGLLAEALGQAVEAAAGAAGRLAREDPALLVAAIRVAEVETERTILGQAPRDWRQRCLRALQEGLERVHFASPVLPEPGALAGWLEALQVALPAELATAEALVAPCCPPSYRVVELWAHTLHSGLRRSVQQLLAGPELGAADTFALLHWALHVYTGKEMMGNLELGPEADVSQLEPLLT | ||||||
Region | 698-718 | Disordered | ||||
Sequence: AALSSLQAGPPPSPSTGRRAL |
Sequence similarities
Belongs to the SEC6 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length739
- Mass (Da)81,204
- Last updated2003-03-01 v1
- Checksum22C9DBED29D8DC31
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1D5RLD9 | A0A1D5RLD9_MOUSE | Exoc3l | 39 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK050100 EMBL· GenBank· DDBJ | BAC34066.1 EMBL· GenBank· DDBJ | mRNA | ||
AK140526 EMBL· GenBank· DDBJ | BAE24415.1 EMBL· GenBank· DDBJ | mRNA | ||
BC094238 EMBL· GenBank· DDBJ | AAH94238.1 EMBL· GenBank· DDBJ | mRNA |