Q8AWE1 · Q8AWE1_DANRE

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componentsynapse
Molecular Functionalpha2-adrenergic receptor activity
Molecular Functiondopamine neurotransmitter receptor activity, coupled via Gi/Go
Molecular FunctionG protein-coupled receptor activity
Biological Processadenylate cyclase-activating adrenergic receptor signaling pathway
Biological Processadenylate cyclase-inhibiting adrenergic receptor signaling pathway
Biological Processadenylate cyclase-inhibiting dopamine receptor signaling pathway
Biological Processnegative regulation of cytosolic calcium ion concentration
Biological Processnegative regulation of synaptic transmission, glutamatergic
Biological Processphospholipase C-activating dopamine receptor signaling pathway
Biological Processpositive regulation of MAPK cascade
Biological Processregulation of dopamine secretion
Biological Processregulation of potassium ion transport

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • D(3) dopamine receptor
    • Dopamine D3 receptor

Gene names

    • Name
      drd3

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q8AWE1

Proteomes

    • Identifier
    • Component
      Alternate scaffold 24, Chromosome 24

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane37-61Helical
Transmembrane73-92Helical
Transmembrane112-133Helical
Transmembrane154-174Helical
Transmembrane194-219Helical
Transmembrane384-405Helical

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain52-437G-protein coupled receptors family 1 profile

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Keywords

Phylogenomic databases

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Complete
  • Length
    454
  • Mass (Da)
    50,895
  • Last updated
    2003-03-01 v1
  • Checksum
    91F48A804587F67F
MAMFSSGEWLWNDSEHSFTPGGNYSPASGVEEAKRNYYAMLYSLLILAIVFGNVLVCIAVLRERALQTTTNYLVVSLAVADLLVASLVMPWAVYLEVVGGAWLFSRLYCNVFVTLDVMMCTASILNLCAISIDRYTAVVMPVLYNTTHSSRKRVSVMIATVWVLAFAVSCPLLFGFNTTDDPAVCSISNPDFVIYSSVVSFYLPFAVTLLVYVRIYIFLRRRRKKITFRQGSGKVQPASAPPSVETCLQDDAHKEKRDLSPIRINVITESKEQVIRPRLLANCLRRKRPQTAPAENSLLPPVITLNYCSISQASFARTEQDANREEEEGGDEEQVAVRGCEVKKLANGRTHTSLRPPRAAHAMVCPSQARCRSMHSKEKKATQMLAIVLGVFLICWLPFFVTHILNTHCRACHIPPEVYSAFTWLGYVNSALNPVIYTTFNIEFRRAFIKILSC

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
F1QG18F1QG18_DANREdrd3472
A0A8M9PTW6A0A8M9PTW6_DANREdrd3467

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY183455
EMBL· GenBank· DDBJ
AAN87173.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp