Q8A5K5 · Q8A5K5_BACTN
- ProteintRNA-specific adenosine deaminase
- GenetadA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids147 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
Catalytic activity
- adenosine34 in tRNA + H+ + H2O = inosine34 in tRNA + NH4+
RHEA-COMP:10373 CHEBI:74411 Position: 34+ CHEBI:15378 + CHEBI:15377 = RHEA-COMP:10374 CHEBI:82852 Position: 34+ CHEBI:28938
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | tRNA-specific adenosine-34 deaminase activity | |
Molecular Function | zinc ion binding | |
Biological Process | tRNA wobble adenosine to inosine editing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-specific adenosine deaminase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides
Accessions
- Primary accessionQ8A5K5
Proteomes
PTM/Processing
Proteomic databases
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-114 | CMP/dCMP-type deaminase | ||||
Sequence: LDDTYFMKQALIEAGKAAERGEVPVGAVVVCKERIIARAHNLTETLNDVTAHAEMQAITAAANVLGGKYLNECTLYVTVEPCVMCAGAIAWAQTGKLVFGAEDDKRGYQRY |
Sequence similarities
Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length147
- Mass (Da)15,971
- Last updated2003-06-01 v1
- Checksum3A072D8ED1686443
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE015928 EMBL· GenBank· DDBJ | AAO77341.1 EMBL· GenBank· DDBJ | Genomic DNA |