Q8A520 · Q8A520_BACTN
- ProteinPotassium-transporting ATPase ATP-binding subunit
- GenekdpB
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids677 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
Catalytic activity
- ATP + H2O + K+(out) = ADP + H+ + K+(in) + phosphate
CHEBI:30616 + CHEBI:15377 + K+ (out)CHEBI:29103= CHEBI:456216 + CHEBI:15378 + K+ (in)CHEBI:29103+ CHEBI:43474
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 304 | 4-aspartylphosphate intermediate | ||||
Sequence: D | ||||||
Binding site | 341 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 345 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 373-380 | ATP (UniProtKB | ChEBI) | ||||
Sequence: FTAETKCS | ||||||
Binding site | 392 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 515 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 519 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | P-type potassium transmembrane transporter activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePotassium-transporting ATPase ATP-binding subunit
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides
Accessions
- Primary accessionQ8A520
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 35-56 | Helical | ||||
Sequence: PIMYTVEVATVVMLFVTLYSII | ||||||
Transmembrane | 62-83 | Helical | ||||
Sequence: SFAYNIAVFIILFITLLFANFA | ||||||
Transmembrane | 216-240 | Helical | ||||
Sequence: IALTILLAGFTLVFVIVCVTLKPFA | ||||||
Transmembrane | 246-271 | Helical | ||||
Sequence: VITIASLISLFVCLIPTTIGGLLSAI | ||||||
Transmembrane | 584-607 | Helical | ||||
Sequence: YFAIVPALFMVAIPELAALNIMQL | ||||||
Transmembrane | 613-631 | Helical | ||||
Sequence: AILSAVIFNAIIIPILIPL | ||||||
Transmembrane | 651-676 | Helical | ||||
Sequence: LLIYGVGGVIAPFIGIKLIDLLVGLF |
Keywords
- Cellular component
PTM/Processing
Interaction
Subunit
The system is composed of three essential subunits: KdpA, KdpB and KdpC.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length677
- Mass (Da)72,448
- Last updated2003-06-01 v1
- Checksum3FFFC7B5762A1ADE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE015928 EMBL· GenBank· DDBJ | AAO77531.1 EMBL· GenBank· DDBJ | Genomic DNA |