Q89Z03 · FLUC_BACTN

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site76Na+ (UniProtKB | ChEBI); structural
Binding site79Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionfluoride transmembrane transporter activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride
Biological Processfluoride transmembrane transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      fluC
    • Synonyms
      crcB
    • Ordered locus names
      BT_4574

Organism names

Accessions

  • Primary accession
    Q89Z03

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane2-22Helical
Transmembrane36-56Helical
Transmembrane69-89Helical
Transmembrane97-117Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001100581-124Fluoride-specific ion channel FluC

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    124
  • Mass (Da)
    14,049
  • Last updated
    2003-06-16 v1
  • Checksum
    DE15F0EEA59C301E
MLKTLLFIGMGSFTGGVLRYLISRYVQNFLTPSFPLGTLLVNVLGCFAIGLFYGLFERGNLMNPNLRMFLTVGFCGGFTTFSTFMNENFQLIKDDNFFYLSLYVGLSLFVGFIMLYLGYSLVKQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE015928
EMBL· GenBank· DDBJ
AAO79679.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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