Q89YT0 · END4_BACTN
- ProteinProbable endonuclease 4
- Genenfo
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids277 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
Catalytic activity
Cofactor
Note: Binds 3 Zn2+ ions.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 69 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 109 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 145 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 145 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 179 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 182 | Zn2+ 3 (UniProtKB | ChEBI) | |||
Binding site | 214 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 227 | Zn2+ 3 (UniProtKB | ChEBI) | |||
Binding site | 229 | Zn2+ 3 (UniProtKB | ChEBI) | |||
Binding site | 259 | Zn2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | deoxyribonuclease IV (phage-T4-induced) activity | |
Molecular Function | DNA binding | |
Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | |
Molecular Function | phosphoric diester hydrolase activity | |
Molecular Function | zinc ion binding | |
Biological Process | base-excision repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable endonuclease 4
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides
Accessions
- Primary accessionQ89YT0
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000190826 | 1-277 | Probable endonuclease 4 | ||
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length277
- Mass (Da)31,540
- Last updated2003-06-01 v1
- Checksum71319F89A904BE91
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE015928 EMBL· GenBank· DDBJ | AAO79756.1 EMBL· GenBank· DDBJ | Genomic DNA |