Q89A21 · REP_BUCBP
- ProteinATP-dependent DNA helicase Rep
- Generep
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids670 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 22-29 | ATP (UniProtKB | ChEBI) | |||
Binding site | 275 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 3'-5' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | isomerase activity | |
Molecular Function | single-stranded DNA binding | |
Biological Process | DNA unwinding involved in DNA replication | |
Biological Process | recombinational repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase Rep
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Erwiniaceae > Buchnera
Accessions
- Primary accessionQ89A21
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000102067 | 1-670 | ATP-dependent DNA helicase Rep | ||
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-277 | UvrD-like helicase ATP-binding | |||
Domain | 278-562 | UvrD-like helicase C-terminal | |||
Sequence similarities
Belongs to the helicase family. UvrD subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length670
- Mass (Da)78,501
- Last updated2003-06-16 v1
- ChecksumA93A1AA1A3869720
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016826 EMBL· GenBank· DDBJ | AAO27239.1 EMBL· GenBank· DDBJ | Genomic DNA |