Q89A21 · REP_BUCBP

Function

function

Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

Catalytic activity

Features

Showing features for binding site.

167050100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site22-29ATP (UniProtKB | ChEBI)
Binding site275ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function3'-5' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionisomerase activity
Molecular Functionsingle-stranded DNA binding
Biological ProcessDNA unwinding involved in DNA replication
Biological Processrecombinational repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase Rep
  • EC number
  • Alternative names
    • DNA 3'-5' helicase Rep

Gene names

    • Name
      rep
    • Ordered locus names
      bbp_540

Organism names

Accessions

  • Primary accession
    Q89A21

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001020671-670ATP-dependent DNA helicase Rep

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-277UvrD-like helicase ATP-binding
Domain278-562UvrD-like helicase C-terminal

Sequence similarities

Belongs to the helicase family. UvrD subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    670
  • Mass (Da)
    78,501
  • Last updated
    2003-06-16 v1
  • Checksum
    A93A1AA1A3869720
MLFNEHQKKAISYISGPCLILAGAGSGKTRVIINKIVHLIKICHFDPKCITAITFTNKAACEMKSRILNVLSVNVSNLVKISTFHALGLEIIKSEIELLNIKSNFTIFDEQDQISILQEIVSKEDRSFVRQIRQSISNWKNKLLCPNQVNKISNSSIEFKFFRYYELYNAYLKSSNILDFDDLIFLPTILLRDNKLSRERWNDKIKYLLVDEYQDTNFIQYKLIKLLSSKRSNFTLVGDDDQSIYSWRGANIHNFESLKHDYPNLRTIIMQHNYRSSGRILKVANALISNNLHFFNKKLFSNLDYGSIVEIISAKNEEDEARVILQTLMLHKSNYNAQYKDYAILYRSNYQVKIFEKFLIKFKIPYKILANISFFSRPEIKDLIAYLRLIINPDDNAAFLRVVNRPLRGIGAVTLQKLKEWSKKRNQSFFMASLDIGLESILPVHNLKSLQEFVYLIQTISYQIQLNPIEVLEKLVATIKYEKWLMRSLKFSKLYVASIKNISIVLNWIINELKYKIMNSKKFVMKYLIDIISEFILQNSLNEDIVINNDYVQLMTLHASKGLEFLYVFIVGVEEGVLPYYRNTTMENNIDEERRLAYVGITRAQKKLFLSYAIQRCQYGVVINTKPSRFLRELPQSDILWQKSKILNLNEKNNFLFKAYKKSLKKKLLR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE016826
EMBL· GenBank· DDBJ
AAO27239.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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