Q88Z91 · ISPE_LACPL

Function

function

Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.

Features

Showing features for active site, binding site.

128820406080100120140160180200220240260280
TypeIDPosition(s)Description
Active site10
Binding site94-104ATP (UniProtKB | ChEBI)
Active site136

GO annotations

AspectTerm
Molecular Function4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
Molecular FunctionATP binding
Biological Processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Biological Processphosphorylation
Biological Processterpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
  • EC number
  • Short names
    CMK
  • Alternative names
    • 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase

Gene names

    • Name
      ispE
    • Ordered locus names
      lp_0460

Organism names

Accessions

  • Primary accession
    Q88Z91
  • Secondary accessions
    • F9UU43

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001892261-2884-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the GHMP kinase family. IspE subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    288
  • Mass (Da)
    32,024
  • Last updated
    2003-06-01 v1
  • Checksum
    7DD4AEEB762C11E8
MQIVEKAPAKINLGLDTLFEHPNGDKEWDMVMTSVDLADYVMLESLHTNRIEVVTDSGFLPNDRRNLAFQAVSVLKRYCHVDRGVRIKIRKAIPVAAGLGGGSSDAAAVLRGLNRMWNLHLDLATLARLGLQVDSDVPYCVYSQTAHVTGKGDVVTPLPKLPPMWIILAKPKVSVSTPNILRQVNYERIDQHPNIEALLAGIQQQDFAEIFANMGNVLEPITAKRYPEILQIKRQLLTFGADAAQMSGTGPTVFGVCRKQSRAQRVYNSLKGFCREVYLVRPVNLNEH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL935263
EMBL· GenBank· DDBJ
CCC77963.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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