Q88V16 · MUTS2_LACPL

Function

function

Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.

Features

Showing features for binding site.

1787100200300400500600700
TypeIDPosition(s)Description
Binding site336-343ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionendonuclease activity
Molecular Functionmismatched DNA binding
Biological Processmismatch repair
Biological Processnegative regulation of DNA recombination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Endonuclease MutS2
  • EC number

Gene names

    • Name
      mutS2
    • Ordered locus names
      lp_2271

Organism names

Accessions

  • Primary accession
    Q88V16
  • Secondary accessions
    • F9UQJ0

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000933701-787Endonuclease MutS2

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain712-787Smr

Sequence similarities

Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    787
  • Mass (Da)
    87,220
  • Last updated
    2003-06-01 v1
  • Checksum
    F059F850A3E7BC39
MNSKVLNTLEYQQVKQQLAPYLVSATGQQALNELHPMTSVADIQRALDETNDGAEVYRLKGGIPVARLADIKPHMKRLAIGATLNGSELGQVGRVLRTTRAITRFFAELLEDAPENDIRHLFDEVAELVTLPDVTKRLATAIEGDGHITDEASPELSRIRSNIRRTETEIRNQMGHYTRGHDAKYLSDPIITIRNDRYVIPVKAENRSRFGGIVHDQSASGQTLFIEPQAVMAMNDRLRQNQVAEKQEEQRILEELSNLIAPYQDEIINNAAILGHFDFINAKARYAHDMKATEPAVSPQNEVYLRQARHPLIDPRKVVANDISLGTDYQAMVITGPNTGGKTITLKTLGLLQLMAQSGLFIPVEAGSRVGVYNEIFADIGDEQSIEQNLSTFSSHMENIESFLAQIDAHSLVLVDELGAGTDPQEGAALAIAILDAIGAKGTQVVATTHYPELKAYGFNRPDTINASMEFDEETLKPTYRLLVGIPGRSNALDIAQRLGIPQAIVDQARSLTDTDSQDLNAMIADLVTKRKQVEDEQLHLKTQVADSEKLHRQLKSEFNAYQQRKDQLIEDAKVQANTIVEQSKTKADAIISDLRKKQLASGTATVKENELIDAKGALNALEQQPKLKKNRVLRRAKAQHDFHEGDDVLVKSYGQRGVLMRQMGKHEWEVQLGILKMKISDGDLERVKPEEPKRARATVQSAHASHVSPNLDLRGVRYEDAMTQVDRYIDAALLAGYPSVTIVHGKGTGALREGITNYLKSNRQVKSFHFAAPNHGGNGATEVQFK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL935263
EMBL· GenBank· DDBJ
CCC79479.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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