Q88UT1 · KITH_LACPL
- ProteinThymidine kinase
- Genetdk
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids192 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- thymidine + ATP = dTMP + ADP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 9-16 | ATP (UniProtKB | ChEBI) | ||||
Sequence: GAMNSGKT | ||||||
Binding site | 85-88 | ATP (UniProtKB | ChEBI) | ||||
Sequence: DEAQ | ||||||
Active site | 86 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 143 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 146 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 180 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 183 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | thymidine kinase activity | |
Molecular Function | zinc ion binding | |
Biological Process | DNA biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | thymidine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThymidine kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lactiplantibacillus
Accessions
- Primary accessionQ88UT1
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000174984 | 1-192 | Thymidine kinase | |||
Sequence: MAQLFFRYGAMNSGKTIEILKVAHNYEEQDKSVIILTSGLDNRDGVGYVASRIGLKREATPVFDDTNIFEIVKQTNPDAACVLIDEAQFLKKHHVLELADIVDELKIPVMTFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCRKKAIMNLRFHDGQPVYEGEQVQIGGNEAYYPVCRHHYFYPPKLTK |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length192
- Mass (Da)22,147
- Last updated2003-06-01 v1
- ChecksumFB4E51939625CEBC
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL935263 EMBL· GenBank· DDBJ | CCC79565.1 EMBL· GenBank· DDBJ | Genomic DNA |