Q88AB2 · MASZ1_PSESM
- ProteinMalate synthase G 1
- GeneglcB1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids725 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
Catalytic activity
- glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H+
Cofactor
Pathway
Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 118 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 125-126 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 276 | acetyl-CoA (UniProtKB | ChEBI) | |||
Binding site | 313 | acetyl-CoA (UniProtKB | ChEBI) | |||
Active site | 340 | Proton acceptor | |||
Binding site | 340 | glyoxylate (UniProtKB | ChEBI) | |||
Binding site | 432 | glyoxylate (UniProtKB | ChEBI) | |||
Binding site | 432 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 457-460 | glyoxylate (UniProtKB | ChEBI) | |||
Binding site | 460 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 541 | acetyl-CoA (UniProtKB | ChEBI) | |||
Active site | 631 | Proton donor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | magnesium ion binding | |
Molecular Function | malate synthase activity | |
Biological Process | glyoxylate catabolic process | |
Biological Process | glyoxylate cycle | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMalate synthase G 1
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionQ88AB2
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000166894 | 1-725 | Malate synthase G 1 | ||
Modified residue | 617 | Cysteine sulfenic acid (-SOH) | |||
Keywords
- PTM
Interaction
Structure
Sequence
- Sequence statusComplete
- Length725
- Mass (Da)79,144
- Last updated2003-04-30 v1
- MD5 Checksum3E63BE17C06D82EF5F6BAC04D5EAFD2F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016853 EMBL· GenBank· DDBJ | AAO54024.1 EMBL· GenBank· DDBJ | Genomic DNA |