Q884N3 · SPEE_PSESM
- ProteinPolyamine aminopropyltransferase
- GenespeE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids286 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
Catalytic activity
- S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H+
Pathway
Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 30 | S-methyl-5'-thioadenosine (UniProtKB | ChEBI) | |||
Binding site | 61 | spermidine (UniProtKB | ChEBI) | |||
Binding site | 85 | spermidine (UniProtKB | ChEBI) | |||
Binding site | 105 | S-methyl-5'-thioadenosine (UniProtKB | ChEBI) | |||
Binding site | 137-138 | S-methyl-5'-thioadenosine (UniProtKB | ChEBI) | |||
Active site | 155 | Proton acceptor | |||
Binding site | 155-158 | spermidine (UniProtKB | ChEBI) | |||
Binding site | 162 | S-methyl-5'-thioadenosine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | spermidine synthase activity | |
Biological Process | spermidine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyamine aminopropyltransferase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionQ884N3
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000156499 | 1-286 | Polyamine aminopropyltransferase | ||
Interaction
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length286
- Mass (Da)32,055
- Last updated2003-06-01 v1
- MD5 Checksum898754F819E23978773FDF9CC6816C24
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016853 EMBL· GenBank· DDBJ | AAO55573.1 EMBL· GenBank· DDBJ | Genomic DNA |