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Q87TT8 · GLMS_PSESM

Function

function

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.

Catalytic activity

Features

Showing features for active site.

161150100150200250300350400450500550600
TypeIDPosition(s)Description
Active site2Nucleophile; for GATase activity
Active site606For Fru-6P isomerization activity

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncarbohydrate derivative binding
Molecular Functionglutamine-fructose-6-phosphate transaminase (isomerizing) activity
Biological Processcarbohydrate metabolic process
Biological Processfructose 6-phosphate metabolic process
Biological Processglutamine metabolic process
Biological Processprotein N-linked glycosylation
Biological ProcessUDP-N-acetylglucosamine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
  • EC number
  • Alternative names
    • D-fructose-6-phosphate amidotransferase
    • GFAT
    • Glucosamine-6-phosphate synthase
    • Hexosephosphate aminotransferase
    • L-glutamine--D-fructose-6-phosphate amidotransferase

Gene names

    • Name
      glmS
    • Ordered locus names
      PSPTO_5595

Organism names

Accessions

  • Primary accession
    Q87TT8

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine, chain.

Type
IDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00001353692-611Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-219Glutamine amidotransferase type-2
Domain287-427SIS 1
Domain460-601SIS 2

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    611
  • Mass (Da)
    66,433
  • Last updated
    2007-01-23 v2
  • MD5 Checksum
    A56D11C483C9E37FC5D8A8B86D609781
MCGIVGAVAERNITAILLEGLKRLEYRGYDSAGVAVFTNEGVLERRRRSGKVSELEQALAGEPLIGRLGIAHTRWATHGAPCERNAHPHFSADELAVVHNGIIENHEALREQLKSLGYVFVSDTDTEVIVHLLHHKLKDTPDLAVALKSAVKELHGAYGLAVINAAQPDRLLAARSGSPLVIGVGMGENFLASDQLALRQVTDRFMYLEEGDIAEIRRDSVQIWTVDGLPVVREVVQYHEGAEAADKGEYRHFMLKEIHEQPKVVQRTLEGRLGQHQVLVHAFGPQAAELFAKVRNVQIVACGTSYHAGMVARYWLEGLAGIPCQVEVASEFRYRKVVVQPDTLFVSISQSGETADTLAALRNAKELGFLASLAICNVGISSLVRESDLTLLTQAGPEIGVASTKAFTTQLVALLLLTLSLGQVKGSLEEGVEAQLVEELRRLPTRLGEALAMDGTIEKVAELFAEKHHTLFLGRGAQFPVAMEGALKLKEISYIHAEAYPAGELKHGPLALVDADMPVVTVAPNNELLEKLKSNLQEVRARGGELIVFADEQAGMKNGEGTHVIAMPHIIDALAPILYTIPLQLLSYYVAVLKGTDVDQPRNLAKSVTVE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE016853
EMBL· GenBank· DDBJ
AAO59008.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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