Q87TT8 · GLMS_PSESM
- ProteinGlutamine--fructose-6-phosphate aminotransferase [isomerizing]
- GeneglmS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids611 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
Catalytic activity
- D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 2 | Nucleophile; for GATase activity | |||
Active site | 606 | For Fru-6P isomerization activity | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | carbohydrate derivative binding | |
Molecular Function | glutamine-fructose-6-phosphate transaminase (isomerizing) activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | fructose 6-phosphate metabolic process | |
Biological Process | glutamine metabolic process | |
Biological Process | protein N-linked glycosylation | |
Biological Process | UDP-N-acetylglucosamine metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamine--fructose-6-phosphate aminotransferase [isomerizing]
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionQ87TT8
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for initiator methionine, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Initiator methionine | 1 | Removed | |||
Chain | PRO_0000135369 | 2-611 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] | ||
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 2-219 | Glutamine amidotransferase type-2 | |||
Domain | 287-427 | SIS 1 | |||
Domain | 460-601 | SIS 2 | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length611
- Mass (Da)66,433
- Last updated2007-01-23 v2
- MD5 ChecksumA56D11C483C9E37FC5D8A8B86D609781
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016853 EMBL· GenBank· DDBJ | AAO59008.1 EMBL· GenBank· DDBJ | Genomic DNA |