Q87EI2 · LPXD_XYLFT
- ProteinUDP-3-O-acylglucosamine N-acyltransferase
- GenelpxD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids338 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Catalytic activity
- a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a (3R)-hydroxyacyl-[ACP] = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + holo-[ACP] + H+
Pathway
Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 239 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | N-acyltransferase activity | |
Biological Process | lipid A biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-3-O-acylglucosamine N-acyltransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Xylella
Accessions
- Primary accessionQ87EI2
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000059715 | 1-338 | UDP-3-O-acylglucosamine N-acyltransferase | ||
Interaction
Subunit
Homotrimer.
Structure
Sequence
- Sequence statusComplete
- Length338
- Mass (Da)35,715
- Last updated2003-06-16 v1
- ChecksumCC26436076A95F2E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE009442 EMBL· GenBank· DDBJ | AAO28209.1 EMBL· GenBank· DDBJ | Genomic DNA |