Q87EI2 · LPXD_XYLFT

Function

function

Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

Catalytic activity

Pathway

Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.

Features

Showing features for active site.

133850100150200250300
TypeIDPosition(s)Description
Active site239Proton acceptor

GO annotations

AspectTerm
Molecular FunctionN-acyltransferase activity
Biological Processlipid A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-3-O-acylglucosamine N-acyltransferase
  • EC number

Gene names

    • Name
      lpxD
    • Ordered locus names
      PD_0325

Organism names

Accessions

  • Primary accession
    Q87EI2

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000597151-338UDP-3-O-acylglucosamine N-acyltransferase

Interaction

Subunit

Homotrimer.

Structure

Family & Domains

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxD subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    338
  • Mass (Da)
    35,715
  • Last updated
    2003-06-16 v1
  • Checksum
    CC26436076A95F2E
MPIFTAQELAERFNLQLFGDGNIRIHGVATLTQASPEQLSFLANPRYLTQLPNSRAGVIVLHADDVKAASGAVLIAKDPYVTFAKIATLFDIKPAREAGIHPLATVDPSAHVSPTAHVGAFVSIGARSSIGASCIIGTGSIIGDDCTIDDGSELIARVTLISRVRLGKRVRIHPGAVLGGEGFGLAMESGHWIKIPQLGGVVIGDDCEIGANSCIDRGALDDTVLEEDVHIDNLVQIAHNCRIGAHTAIAGCTGIAGSAKIGRYCLLGGHVGVVGHLQICDNVVITGKSVVRNSIHTPGEYSSGTPLTDNRTWRKNAVRFKQLDMLVRRMMAVSKEKA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE009442
EMBL· GenBank· DDBJ
AAO28209.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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