No title available.Hromas R.A., Ramsey H., Richkind K.Cited forNUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (NOV-2002)Cited in1
Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H.[...], Sugano S.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)TissueHippocampusCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 36:40-45 (2004)Cited in99+99+
The finished DNA sequence of human chromosome 12.Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.[...], Gibbs R.A.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 440:346-351 (2006)Cited in99+99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)TissueBrainCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.[...], Elledge S.J.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-260, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueEmbryonic kidneyCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 316:1160-1166 (2007)Cited in99+99+Mapped to23
A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueCervix carcinomaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 105:10762-10767 (2008)Cited in99+99+
WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac.Miki H., Suetsugu S., Takenawa T.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCEMBO J 17:6932-6941 (1998)Mapped to99+
Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3.Leung I.W.L., Lassam N.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCJ. Biol. Chem. 273:32408-32415 (1998)Cited in1Mapped to91
WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells.Ramesh N., Anton I.M., Hartwig J.H., Geha R.S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 94:14671-14676 (1997)Cited in2Mapped to58
Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5- bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha.Hammond S.M., Jenco J.M., Nakashima S., Cadwallader K., Gu Q.-M., Cook S., Nozawa Y., Prestwich G.D., Frohman M.A., Morris A.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCJ. Biol. Chem. 272:3860-3868 (1997)Cited in1Mapped to99+
The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton.Leung T., Chen X.-Q., Manser E., Lim L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCMol. Cell. Biol. 16:5313-5327 (1996)Cited in4Mapped to99+
Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome.Aspenstrom P., Lindberg U., Hall A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCCurr Biol 6:70-75 (1996)Mapped to99+
Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1.Kuroda S., Fukata M., Kobayashi K., Nakafuku M., Nomura N., Iwamatsu A., Kaibuchi K.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCJ Biol Chem 271:23363-23367 (1996)Mapped to99+
The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.Brill S., Li S., Lyman C.W., Church D.M., Wasmuth J.J., Weissbach L., Bernards A., Snijders A.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCMol. Cell. Biol. 16:4869-4878 (1996)Cited in1Mapped to99+
IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs.Hart M.J., Callow M.G., Souza B., Polakis P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCEMBO J. 15:2997-3005 (1996)Cited in1Mapped to62
Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain.Reid T., Furuyashiki T., Ishizaki T., Watanabe G., Watanabe N., Fujisawa K., Morii N., Madaule P., Narumiya S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCJ. Biol. Chem. 271:13556-13560 (1996)Cited in4Mapped to99+
<i>CPNE8</i> Promotes Gastric Cancer Metastasis by Modulating Focal Adhesion Pathway and Tumor Microenvironment.Zhang P., Cao X., Guan M., Li D., Xiang H., Peng Q., Zhou Y., Weng C., Fang X.[...], Lu L.View abstractAnnotationCPNE8 Promotes Gastric Cancer Metastasis by Modulating Focal Adhesion Pathway and Tumor Microenvironment.CategoriesFunction, ExpressionSourceGeneRif: 144402PubMedEurope PMCInt J Biol Sci 18:4932-4949 (2022)Mapped to2
RhoJ Regulates alpha5beta1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.Sundararaman A., Fukushima Y., Norman J.C., Uemura A., Mellor H.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCCurr Biol 30:2146-2155.e5 (2020)Mapped to58
Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms.Bagci H., Sriskandarajah N., Robert A., Boulais J., Elkholi I.E., Tran V., Lin Z.Y., Thibault M.P., Dube N.[...], Cote J.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCNat. Cell Biol. 22:120-134 (2020)Cited in2Mapped to99+
FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis.Chan Wah Hak L., Khan S., Di Meglio I., Law A.L., Lucken-Ardjomande Hasler S., Quintaneiro L.M., Ferreira A.P.A., Krause M., McMahon H.T., Boucrot E.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCNat Cell Biol 20:1023-1031 (2018)Mapped to75
A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.Amado-Azevedo J., Reinhard N.R., van Bezu J., de Menezes R.X., van Beusechem V.W., van Nieuw Amerongen G.P., van Hinsbergh V.W.M., Hordijk P.L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCSci Rep 7:10132-10132 (2017)Mapped to99+
An apical MRCK-driven morphogenetic pathway controls epithelial polarity.Zihni C., Vlassaks E., Terry S., Carlton J., Leung T.K.C., Olson M., Pichaud F., Balda M.S., Matter K.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCNat Cell Biol 19:1049-1060 (2017)Mapped to69
RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.Durkin C.H., Leite F., Cordeiro J.V., Handa Y., Arakawa Y., Valderrama F., Way M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCDev Cell 41:315-329.e7 (2017)Mapped to29
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.Gupta G.D., Coyaud E., Goncalves J., Mojarad B.A., Liu Y., Wu Q., Gheiratmand L., Comartin D., Tkach J.M.[...], Pelletier L.View abstractCategoriesInteractionSourceIntAct: Q86YQ8PubMedEurope PMCCell 163:1484-1499 (2015)Cited in9Mapped to99+
PAK6 targets to cell-cell adhesions through its N-terminus in a Cdc42- dependent manner to drive epithelial colony escape.Morse E.M., Sun X., Olberding J.R., Ha B.H., Boggon T.J., Calderwood D.A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-9714847PubMedEurope PMCJ Cell Sci 129:380-393 (2016)Mapped to65