Q86VY9 · T200A_HUMAN

  • Protein
    Transmembrane protein 200A
  • Gene
    TMEM200A
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Transmembrane protein 200A

Gene names

    • Name
      TMEM200A
    • Synonyms
      KIAA1913
    • ORF names
      HBE61

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q86VY9
  • Secondary accessions
    • Q96PX5

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-61Cytoplasmic
Transmembrane62-82Helical
Topological domain83-126Extracellular
Transmembrane127-147Helical
Topological domain148-491Cytoplasmic

Keywords

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 760 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Miscellaneous

Genetic variation databases

PTM/Processing

Features

Showing features for chain, modified residue (large scale data), glycosylation, modified residue.

TypeIDPosition(s)SourceDescription
ChainPRO_00002943401-491UniProtTransmembrane protein 200A
Modified residue (large scale data)19PRIDEPhosphoserine
Modified residue (large scale data)22PRIDEPhosphoserine
Modified residue (large scale data)29PRIDEPhosphoserine
Modified residue (large scale data)31PRIDEPhosphoserine
Glycosylation100UniProtN-linked (GlcNAc...) asparagine
Modified residue (large scale data)224PRIDEPhosphoserine
Modified residue (large scale data)225PRIDEPhosphoserine
Modified residue (large scale data)323PRIDEPhosphoserine
Modified residue (large scale data)326PRIDEPhosphoserine
Modified residue350UniProtPhosphoserine
Modified residue (large scale data)350PRIDEPhosphoserine
Modified residue (large scale data)359PRIDEPhosphotyrosine
Modified residue (large scale data)362PRIDEPhosphoserine
Modified residue (large scale data)374PRIDEPhosphoserine
Modified residue (large scale data)384PRIDEPhosphoserine
Modified residue (large scale data)397PRIDEPhosphoserine
Modified residue (large scale data)466PRIDEPhosphoserine
Modified residue (large scale data)471PRIDEPhosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in cerebellum.

Gene expression databases

Organism-specific databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q86VY9BCL2L10 Q9HD363EBI-11732844, EBI-2126349
BINARY Q86VY9EMD P504023EBI-11732844, EBI-489887
BINARY Q86VY9UNC119 Q134323EBI-11732844, EBI-711260

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias16-34Polar residues
Region16-41Disordered

Sequence similarities

Belongs to the TMEM200 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    491
  • Mass (Da)
    54,356
  • Last updated
    2003-06-01 v1
  • Checksum
    EEFFF8CDAC4DB610
MIATGGVITGLAALKRQDSARSQQHVNLSPSPATQEKKPIRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVIRNEGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQRQMNGMYTGLMGETEVKQNGSSCASRLAANTIASFSGFRSSFRMDSSVEEDELMLNEGKSSGHLMPPLLSDSSVSVFGLYPPPSKTTDDKTSGSKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDADNLKSRSRNLSMDSLVVPLPNTSESFQPVSTVLPRNNSIGESLSSQYKSSMALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWPRLDRNNSKGYMKLENKEDPMDRLLVPQVAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF

Sequence caution

The sequence BAB67806.1 differs from that shown. Reason: Erroneous initiation

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias16-34Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB052099
EMBL· GenBank· DDBJ
BAD05135.1
EMBL· GenBank· DDBJ
mRNA
AB067500
EMBL· GenBank· DDBJ
BAB67806.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AL137251
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BC044246
EMBL· GenBank· DDBJ
AAH44246.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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