Q86V59 · PNM8A_HUMAN
- ProteinParaneoplastic antigen-like protein 8A
- GenePNMA8A
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids439 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameParaneoplastic antigen-like protein 8A
- Alternative names
Gene names
- Community suggested namesPNMA8A
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ86V59
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_039935 | 80 | in dbSNP:rs12610254 | |||
Sequence: S → T | ||||||
Natural variant | VAR_039936 | 97 | in dbSNP:rs7248888 | |||
Sequence: C → Y |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 563 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000325836 | 1-439 | Paraneoplastic antigen-like protein 8A | |||
Sequence: MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAAEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRGPKAKPEGSPRRATNESRKV |
Proteomic databases
PTM databases
Expression
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 208-439 | Disordered | ||||
Sequence: SALKAETPNNWNATEDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRGPKAKPEGSPRRATNESRKV | ||||||
Compositional bias | 235-249 | Basic residues | ||||
Sequence: AGAKSRSRRKKQKKN | ||||||
Compositional bias | 292-306 | Basic and acidic residues | ||||
Sequence: RKPCVNKEELALKKP | ||||||
Compositional bias | 378-403 | Basic and acidic residues | ||||
Sequence: DSEDGRKKPVMPKKGPGSRREASDQK | ||||||
Compositional bias | 424-439 | Basic and acidic residues | ||||
Sequence: KPEGSPRRATNESRKV |
Sequence similarities
Belongs to the PNMA family.
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q86V59-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length439
- Mass (Da)48,161
- Last updated2004-12-07 v2
- Checksum43E43FA1CAEC1E81
Q86V59-2
- Name2
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
M0R388 | M0R388_HUMAN | PNMA8A | 84 |
Sequence caution
Features
Showing features for compositional bias, sequence conflict, alternative sequence.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 235-249 | Basic residues | ||||
Sequence: AGAKSRSRRKKQKKN | ||||||
Compositional bias | 292-306 | Basic and acidic residues | ||||
Sequence: RKPCVNKEELALKKP | ||||||
Sequence conflict | 319 | in Ref. 3; AAH32508 | ||||
Sequence: P → S | ||||||
Alternative sequence | VSP_032441 | 367-378 | in isoform 2 | |||
Sequence: VSLGPVSYVLVD → NPERFDLGDHPY | ||||||
Compositional bias | 378-403 | Basic and acidic residues | ||||
Sequence: DSEDGRKKPVMPKKGPGSRREASDQK | ||||||
Alternative sequence | VSP_032442 | 379-439 | in isoform 2 | |||
Sequence: Missing | ||||||
Compositional bias | 424-439 | Basic and acidic residues | ||||
Sequence: KPEGSPRRATNESRKV |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL834344 EMBL· GenBank· DDBJ | CAD39010.1 EMBL· GenBank· DDBJ | mRNA | ||
CH471126 EMBL· GenBank· DDBJ | EAW57420.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation | |
CH471126 EMBL· GenBank· DDBJ | EAW57421.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC026026 EMBL· GenBank· DDBJ | AAH26026.2 EMBL· GenBank· DDBJ | mRNA | ||
BC032508 EMBL· GenBank· DDBJ | AAH32508.1 EMBL· GenBank· DDBJ | mRNA | ||
BC051688 EMBL· GenBank· DDBJ | AAH51688.2 EMBL· GenBank· DDBJ | mRNA | ||
AK001643 EMBL· GenBank· DDBJ | BAA91804.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
AK290218 EMBL· GenBank· DDBJ | BAF82907.1 EMBL· GenBank· DDBJ | mRNA | Sequence problems. |