A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development.Morita M., Ler L.W., Fabian M.R., Siddiqui N., Mullin M., Henderson V.C., Alain T., Fonseca B.D., Karashchuk G.[...], Sonenberg N.View abstractCited forFUNCTION, IDENTIFICATION IN THE 4EHP-GYF2 COMPLEXCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Biol. 32:3585-3593 (2012)Cited in4Mapped to42
Initiation of quality control during poly(A) translation requires site- specific ribosome ubiquitination.Juszkiewicz S., Hegde R.S.View abstractCited forFUNCTION, CATALYTIC ACTIVITY, PATHWAYCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 65:743-750 (2016)Cited in4
ZNF598 and RACK1 regulate mammalian ribosome-associated quality control function by mediating regulatory 40S ribosomal ubiquitylation.Sundaramoorthy E., Leonard M., Mak R., Liao J., Fulzele A., Bennett E.J.View abstractCited forFUNCTION, CATALYTIC ACTIVITY, PATHWAY, MUTAGENESIS OF CYS-29CategoriesFunction, Disease & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 65:751-760 (2017)Cited in6Mapped to7
The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.Garzia A., Jafarnejad S.M., Meyer C., Chapat C., Gogakos T., Morozov P., Amiri M., Shapiro M., Molina H.[...], Sonenberg N.View abstractCited forFUNCTION, CATALYTIC ACTIVITY, PATHWAY, INTERACTION WITH UBE2D3CategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Commun. 8:16056-16056 (2017)Cited in4Mapped to3
ZNF598 plays distinct roles in interferon-stimulated gene expression and poxvirus protein synthesis.DiGiuseppe S., Rollins M.G., Bartom E.T., Walsh D.View abstractCited forFUNCTION, FUNCTION (MICROBIAL INFECTION)CategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Rep. 23:1249-1258 (2018)Cited in1Mapped to2
ZNF598 is a quality control sensor of collided ribosomes.Juszkiewicz S., Chandrasekaran V., Lin Z., Kraatz S., Ramakrishnan V., Hegde R.S.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 72:469-481 (2018)Cited in554
The ASC-1 complex disassembles collided ribosomes.Juszkiewicz S., Speldewinde S.H., Wan L., Svejstrup J.Q., Hegde R.S.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 79:603-614 (2020)Cited in4
GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control.Hickey K.L., Dickson K., Cogan J.Z., Replogle J.M., Schoof M., D'Orazio K.N., Sinha N.K., Hussmann J.A., Jost M.[...], Kostova K.K.View abstractCited forFUNCTION, IDENTIFICATION IN THE 4EHP-GYF2 COMPLEXCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 79:950.e6-962.e6 (2020)Cited in4Mapped to10
Identification of a novel trigger complex that facilitates ribosome- associated quality control in mammalian cells.Hashimoto S., Sugiyama T., Yamazaki R., Nobuta R., Inada T.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCSci. Rep. 10:3422-3422 (2020)Cited in4
Live-cell imaging reveals kinetic determinants of quality control triggered by ribosome stalling.Goldman D.H., Livingston N.M., Movsik J., Wu B., Green R.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 81:1830-1840 (2021)Cited in1
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.Narita M., Denk T., Matsuo Y., Sugiyama T., Kikuguchi C., Ito S., Sato N., Suzuki T., Hashimoto S.[...], Inada T.View abstractCited forFUNCTION, CATALYTIC ACTIVITY, PATHWAYCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Commun. 13:6411-6411 (2022)Cited in635Mapped to41