Q86UE9 · Q86UE9_HUMAN

  • Protein
    Solute carrier family 15 member 2
  • Gene
    SLC15A2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

Catalytic activity

  • 2 H+(out) + L-alanyl-L-alanine(out) = 2 H+(in) + L-alanyl-L-alanine(in)
    This reaction proceeds in the forward direction.
  • 3 H+(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) = 3 H+(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)
    This reaction proceeds in the forward direction.
  • a dipeptide(out) + 2 H+(out) = a dipeptide(in) + 2 H+(in)
    This reaction proceeds in the forward direction.
  • an L-amino acid tripeptide(out) + 2 H+(out) = an L-amino acid tripeptide(in) + 2 H+(in)
    This reaction proceeds in the forward direction.
  • carnosine(out) + 2 H+(out) = carnosine(in) + 2 H+(in)
    This reaction proceeds in the forward direction.
  • glycyl-L-glutamate(out) + 3 H+(out) = glycyl-L-glutamate(in) + 3 H+(in)
    This reaction proceeds in the forward direction.
  • glycyl-L-leucine(out) + 2 H+(out) = glycyl-L-leucine + 2 H+(in)
    This reaction proceeds in the forward direction.
  • glycyl-L-lysine(out) + 2 H+(out) = glycyl-L-lysine(in) + 2 H+(in)
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentphagocytic vesicle membrane
Molecular Functiondipeptide transmembrane transporter activity
Molecular Functionsymporter activity
Biological Processdipeptide import across plasma membrane
Biological Processinnate immune response
Biological Processpeptide transport
Biological Processprotein transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Solute carrier family 15 member 2
  • Alternative names
    • Peptide transporter 2

Gene names

    • Name
      SLC15A2

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q86UE9

Subcellular Location

Apical cell membrane
; Multi-pass membrane protein
Cell membrane
; Multi-pass membrane protein
Cytoplasmic vesicle, phagosome membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane58-78Helical
Transmembrane84-104Helical
Transmembrane116-137Helical
Transmembrane143-164Helical
Transmembrane185-205Helical
Transmembrane217-237Helical
Transmembrane298-316Helical
Transmembrane346-367Helical
Transmembrane379-397Helical
Transmembrane647-669Helical
Transmembrane675-697Helical

Keywords

PTM/Processing

Keywords

Proteomic databases

Interaction

Subunit

Interacts (via extracellular domain region) with trypsin.

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-34Disordered
Compositional bias20-34Pro residues

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    729
  • Mass (Da)
    81,753
  • Last updated
    2003-06-01 v1
  • Checksum
    017C88004A874E97
MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSYYGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFDFVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLNLADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHSVQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIEDIPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSGMKSVLQAAWLLTIAVGNIIVLVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMIKLETKKTKL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias20-34Pro residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC044572
EMBL· GenBank· DDBJ
AAH44572.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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