Q86I81 · MCFI_DICDI

Function

function

Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports folate across the inner membranes of mitochondria (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrion
Molecular FunctionFAD transmembrane transporter activity
Molecular Functionfolic acid transmembrane transporter activity
Biological Processfolate import into mitochondrion

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Mitochondrial substrate carrier family protein I
  • Alternative names
    • Mitochondrial folate transporter A

Gene names

    • Name
      mcfI
    • Synonyms
      mftA
    • ORF names
      DDB_G0271922

Organism names

Accessions

  • Primary accession
    Q86I81
  • Secondary accessions
    • Q55AF5

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-24Mitochondrial intermembrane
Transmembrane25-45Helical; Name=1
Topological domain46-109Mitochondrial matrix
Transmembrane110-130Helical; Name=2
Topological domain131-158Mitochondrial intermembrane
Transmembrane159-179Helical; Name=3
Topological domain180-203Mitochondrial matrix
Transmembrane204-224Helical; Name=4
Topological domain225-253Mitochondrial intermembrane
Transmembrane254-274Helical; Name=5
Topological domain275-307Mitochondrial matrix
Transmembrane308-328Helical; Name=6
Topological domain329-338Mitochondrial intermembrane

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003855231-338Mitochondrial substrate carrier family protein I

Proteomic databases

Expression

Induction

Regulated by the MADS-box transcription factor srfA during development.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for repeat.

TypeIDPosition(s)Description
Repeat25-139Solcar 1
Repeat153-235Solcar 2
Repeat248-332Solcar 3

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    338
  • Mass (Da)
    36,655
  • Last updated
    2003-06-01 v1
  • Checksum
    E58779BDF7546CA4
MVNGEEYVETPNLIHDEETRKDVKFNLGIELLAGTLAGVSSCILFYPLECVEAKLQVQSSSTAVAATMLGLKKNGGSGSGSSSSSSISHQTPNGPIAMAKSILRNEGFKGFYQGVSPTILGNAVNWGVYFSIYRATNHWWNSTDINGNQYQGPAWVGHSVSAITAGVITTAIVNPFWVLKIRLATSKKYSGMKHAFQSILRSEGVGGFWKGVGVSFIGVSEGLFQFVSYEYILNQMKESNLKMNGGELSVGNYLFAGGTARLIAGVLTYPYLLIRSSLQSETCPYKSMSEAVKGIYKTNGIKGFYKGIGPNLARSIPPAAFMLYIVEFFRDTLTNFSQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY392437
EMBL· GenBank· DDBJ
AAQ98878.1
EMBL· GenBank· DDBJ
Genomic DNA
AAFI02000007
EMBL· GenBank· DDBJ
EAL71485.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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