Q867X6 · CY24A_DICDI

Function

function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentNADPH oxidase complex
Molecular Functionheme binding
Biological Processinnate immune response
Biological Processsorocarp development
Biological Processsuperoxide anion generation

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Superoxide-generating NADPH oxidase light chain subunit
  • Alternative names
    • Cytochrome b-245 light chain
    • p22-phox (p22phox)

Gene names

    • Name
      cybA
    • ORF names
      DDB_G0267460

Organism names

Accessions

  • Primary accession
    Q867X6
  • Secondary accessions
    • Q55GP4

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
Note: As unassembled monomer may localize to the endoplasmic reticulum.

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane9-29Helical
Transmembrane36-56Helical
Transmembrane62-82Helical
Transmembrane83-103Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Prevents formation of fruiting bodies.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003615301-118Superoxide-generating NADPH oxidase light chain subunit

Proteomic databases

Expression

Developmental stage

Expressed during vegetative stage. Expression decreases during development and disappears from 8 hours.

Interaction

Subunit

Composed of a heavy chain and a light chain.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the p22phox family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    118
  • Mass (Da)
    13,008
  • Last updated
    2003-06-01 v1
  • Checksum
    2F07828020A16DBB
MGKFKLGNWAAMIGMAACWCLIAGGIMGIWYERRYIAIYSICVGGVLYPLLYPLSFLGPLKAIFHQYYVAAALMAGLSVLCYFLVPTMLAAMVMDISAVVFLISAIKGERGDFFDKQD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY221170
EMBL· GenBank· DDBJ
AAO62418.1
EMBL· GenBank· DDBJ
mRNA
AY221171
EMBL· GenBank· DDBJ
AAO62419.1
EMBL· GenBank· DDBJ
Genomic DNA
AAFI02000003
EMBL· GenBank· DDBJ
EAL73183.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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