Q861J1 · Q861J1_RAT

  • Protein
    MHC class Ib antigen
  • Gene
    RT1-CE5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Involved in the presentation of foreign antigens to the immune system.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell surface
Cellular Componentearly endosome membrane
Cellular Componentendoplasmic reticulum
Cellular Componentexternal side of plasma membrane
Cellular Componentextracellular space
Cellular ComponentGolgi membrane
Cellular Componentlumenal side of endoplasmic reticulum membrane
Cellular Componentlysosomal membrane
Cellular ComponentMHC class I protein complex
Cellular ComponentMHC class Ib protein complex
Cellular Componentphagocytic vesicle membrane
Cellular Componentplasma membrane
Molecular Function14-3-3 protein binding
Molecular Functionbeta-2-microglobulin binding
Molecular Functionpeptide antigen binding
Molecular Functionsignaling receptor binding
Molecular FunctionTAP1 binding
Molecular FunctionTAP2 binding
Biological Processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
Biological Processantigen processing and presentation of endogenous peptide antigen via MHC class Ib
Biological Processantigen processing and presentation of exogenous peptide antigen via MHC class Ib
Biological Processimmune response
Biological Processnegative regulation of natural killer cell cytokine production
Biological Processnegative regulation of natural killer cell degranulation
Biological Processnegative regulation of natural killer cell mediated cytotoxicity
Biological Processnegative regulation of T cell cytokine production
Biological Processpositive regulation of natural killer cell cytokine production
Biological Processpositive regulation of natural killer cell degranulation
Biological Processpositive regulation of T cell mediated cytotoxicity

Keywords

  • Biological process

Names & Taxonomy

Protein names

  • Submitted names
    • MHC class Ib antigen

Gene names

    • Name
      RT1-CE5
    • Synonyms
      rt1-E2b gene

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • LEW
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    Q861J1

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane288-312Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain185-273Ig-like
Region322-346Disordered
Compositional bias329-346Polar residues

Sequence similarities

Belongs to the MHC class I family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    346
  • Mass (Da)
    39,354
  • Last updated
    2003-06-01 v1
  • Checksum
    04FF0648B468C076
GSHSLRYFHTAVSRPGLREPRFIIVGYVDHTEFVRYDSDAENPRYEPRARWMEREGPEYWEQQTQIVKGHEWSFRVSLRNLLGYYNQSEGGSHTLQVMSGCDMGSDRSLRRGYEQYAYDGRDYISLNEDLKTWSAADLAAQITLNKWDQAGELDYYKAYLEGPCLEWLLRYLEHGKETLMRSDPPKAHVTLHPRPEGDVTLRCWALGFYPADITLTWQLNEEDLTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCLVDHEGLPEPLTLRWEAPPSTNSNTGMSVILGTVTIIAVMAIIVVVAVIRTVVRKRWIKTGGKGDYTPAPGRDSSQSSDVSLPDCKA

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias329-346Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ537417
EMBL· GenBank· DDBJ
CAD60940.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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