Q85KZ3 · Q85KZ3_HUMAN

  • Protein
    ATP synthase protein 8
  • Gene
    ATP8
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentproton-transporting ATP synthase complex, coupling factor F(o)
Molecular Functionproton transmembrane transporter activity
Biological Processproton motive force-driven ATP synthesis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    ATP synthase protein 8

Gene names

    • Name
      ATP8

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • MTDNA336
    • D1367
    • PA_EU_IT_0079
    • N1b2_33002_Pal
    • ATP6/N1b
    • TV20
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q85KZ3

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-36Helical

Keywords

PTM/Processing

Keywords

Proteomic databases

Structure

Family & Domains

Sequence similarities

Belongs to the ATPase protein 8 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    68
  • Mass (Da)
    8,008
  • Last updated
    2003-06-01 v1
  • MD5 Checksum
    AFB9F448655E4F4DC0034C571BF7F7FC
MPQLNTTVWPTMITPMLLTLFLITQLKMLNTNYHLLPSPKPMKMKNYNKPWEPKWTKICSLHSLPPQS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY195756
EMBL· GenBank· DDBJ
AAO88427.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ301794
EMBL· GenBank· DDBJ
ABB91052.1
EMBL· GenBank· DDBJ
Genomic DNA
EF660993
EMBL· GenBank· DDBJ
ABR58574.1
EMBL· GenBank· DDBJ
Genomic DNA
EF657494
EMBL· GenBank· DDBJ
ABR96388.1
EMBL· GenBank· DDBJ
Genomic DNA
EU742148
EMBL· GenBank· DDBJ
ACF03815.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ460561
EMBL· GenBank· DDBJ
ACJ47771.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ493516
EMBL· GenBank· DDBJ
ACJ71045.1
EMBL· GenBank· DDBJ
Genomic DNA
GQ891612
EMBL· GenBank· DDBJ
ACV90380.1
EMBL· GenBank· DDBJ
Genomic DNA
GU122992
EMBL· GenBank· DDBJ
ACY55300.1
EMBL· GenBank· DDBJ
Genomic DNA
HM765456
EMBL· GenBank· DDBJ
ADK66468.1
EMBL· GenBank· DDBJ
Genomic DNA
HM852768
EMBL· GenBank· DDBJ
ADL30054.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ157982
EMBL· GenBank· DDBJ
ADN33602.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ384201
EMBL· GenBank· DDBJ
ADO85110.1
EMBL· GenBank· DDBJ
Genomic DNA
JQ245725
EMBL· GenBank· DDBJ
AEY70870.1
EMBL· GenBank· DDBJ
Genomic DNA
JQ701805
EMBL· GenBank· DDBJ
AFF61427.1
EMBL· GenBank· DDBJ
Genomic DNA
JX153036
EMBL· GenBank· DDBJ
AFO23645.1
EMBL· GenBank· DDBJ
Genomic DNA
KC911348
EMBL· GenBank· DDBJ
AGO91268.1
EMBL· GenBank· DDBJ
Genomic DNA
KF297809
EMBL· GenBank· DDBJ
AGW31737.1
EMBL· GenBank· DDBJ
Genomic DNA
KF451097
EMBL· GenBank· DDBJ
AGZ67898.1
EMBL· GenBank· DDBJ
Genomic DNA
KJ742714
EMBL· GenBank· DDBJ
AIG22785.1
EMBL· GenBank· DDBJ
Genomic DNA
KJ801471
EMBL· GenBank· DDBJ
AIL91985.1
EMBL· GenBank· DDBJ
Genomic DNA
KM101691
EMBL· GenBank· DDBJ
AIU58686.1
EMBL· GenBank· DDBJ
Genomic DNA
KM245141
EMBL· GenBank· DDBJ
AIY56013.1
EMBL· GenBank· DDBJ
Genomic DNA
KM986518
EMBL· GenBank· DDBJ
AJV86964.1
EMBL· GenBank· DDBJ
Genomic DNA
KT819231
EMBL· GenBank· DDBJ
ALM03554.1
EMBL· GenBank· DDBJ
Genomic DNA
KY399199
EMBL· GenBank· DDBJ
AQU13808.1
EMBL· GenBank· DDBJ
Genomic DNA
KX977307
EMBL· GenBank· DDBJ
AQZ25258.1
EMBL· GenBank· DDBJ
Genomic DNA
KY782166
EMBL· GenBank· DDBJ
ASC43281.1
EMBL· GenBank· DDBJ
Genomic DNA
MF362770
EMBL· GenBank· DDBJ
ASF84708.1
EMBL· GenBank· DDBJ
Genomic DNA
MF362884
EMBL· GenBank· DDBJ
ASF86190.1
EMBL· GenBank· DDBJ
Genomic DNA
MF056543
EMBL· GenBank· DDBJ
ASS03990.1
EMBL· GenBank· DDBJ
Genomic DNA
KY797169
EMBL· GenBank· DDBJ
AUG82337.1
EMBL· GenBank· DDBJ
Genomic DNA
MF591562
EMBL· GenBank· DDBJ
AVL92192.1
EMBL· GenBank· DDBJ
Genomic DNA
MG182449
EMBL· GenBank· DDBJ
AXF36333.1
EMBL· GenBank· DDBJ
Genomic DNA
MK059572
EMBL· GenBank· DDBJ
QCB17648.1
EMBL· GenBank· DDBJ
Genomic DNA
MK491383
EMBL· GenBank· DDBJ
QEG55421.1
EMBL· GenBank· DDBJ
Genomic DNA
MK134289
EMBL· GenBank· DDBJ
QGW54056.1
EMBL· GenBank· DDBJ
Genomic DNA
MT079106
EMBL· GenBank· DDBJ
QIV22338.1
EMBL· GenBank· DDBJ
Genomic DNA
MN687119
EMBL· GenBank· DDBJ
QLH90379.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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