Q84ZN6 · CESA8_ORYSJ

Function

function

Probable catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Pathway

Glycan metabolism; plant cellulose biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site19Zn2+ 1 (UniProtKB | ChEBI)
Binding site22Zn2+ 1 (UniProtKB | ChEBI)
Binding site38Zn2+ 2 (UniProtKB | ChEBI)
Binding site41Zn2+ 2 (UniProtKB | ChEBI)
Binding site46Zn2+ 1 (UniProtKB | ChEBI)
Binding site49Zn2+ 1 (UniProtKB | ChEBI)
Binding site61Zn2+ 2 (UniProtKB | ChEBI)
Binding site64Zn2+ 2 (UniProtKB | ChEBI)
Binding site360UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site366UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site367UDP-alpha-D-glucose (UniProtKB | ChEBI)
Active site396
Binding site396UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site537UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site538Mn2+ (UniProtKB | ChEBI)
Binding site562Mn2+ (UniProtKB | ChEBI)
Active site781

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncellulose synthase (UDP-forming) activity
Molecular Functioncellulose synthase activity
Molecular Functionmetal ion binding
Biological Processcell wall organization
Biological Processcellulose biosynthetic process
Biological Processplant-type primary cell wall biogenesis

Keywords

Enzyme and pathway databases

Protein family/group databases

    • GT2Glycosyltransferase Family 2

Names & Taxonomy

Protein names

  • Recommended name
    Probable cellulose synthase A catalytic subunit 8 [UDP-forming]
  • EC number
  • Alternative names
    • OsCesA8

Gene names

    • Name
      CESA8
    • ORF names
      OJ1136_A05.10, OJ1559_F09.120, OsJ_022567
    • Ordered locus names
      Os07g0208500, LOC_Os07g10770

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q84ZN6
  • Secondary accessions
    • B7EKN8

Proteomes

Genome annotation databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-277Cytoplasmic
Transmembrane278-298Helical
Topological domain299-300Extracellular
Transmembrane301-321Helical
Topological domain322-864Cytoplasmic
Transmembrane865-885Helical
Topological domain886-890Extracellular
Transmembrane891-911Helical
Topological domain912-926Cytoplasmic
Transmembrane927-947Helical
Topological domain948-977Extracellular
Transmembrane978-998Helical
Topological domain999-1009Cytoplasmic
Transmembrane1010-1030Helical
Topological domain1031-1039Extracellular
Transmembrane1040-1060Helical
Topological domain1061-1081Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, modified residue (large scale data), glycosylation.

TypeIDPosition(s)SourceDescription
ChainPRO_00003193681-1081UniProtProbable cellulose synthase A catalytic subunit 8 [UDP-forming]
Modified residue (large scale data)91PTMeXchangePhosphoserine
Modified residue (large scale data)131PTMeXchangePhosphoserine
Modified residue (large scale data)141PTMeXchangePhosphoserine
Modified residue (large scale data)189PTMeXchangePhosphoserine
Modified residue (large scale data)197PTMeXchangePhosphoserine
Modified residue (large scale data)718PTMeXchangePhosphoserine
Glycosylation954UniProtN-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for zinc finger, region, coiled coil.

TypeIDPosition(s)Description
Zinc finger19-65RING-type; degenerate
Region72-148Disordered
Coiled coil450-477
Region660-684Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,081
  • Mass (Da)
    120,794
  • Last updated
    2003-06-01 v1
  • Checksum
    BA17F2D40BFAA2EB
MDGDADAVKSGRHGSGQACQICGDGVGTTAEGDVFAACDVCGFPVCRPCYEYERKDGTQACPQCKTKYKRHKGSPAIRGEEGEDTDADDVSDYNYPASGSADQKQKIADRMRSWRMNAGGGGDVGRPKYDSGEIGLTKYDSGEIPRGYIPSVTNSQISGEIPGASPDHHMMSPTGNIGKRAPFPYVNHSPNPSREFSGSIGNVAWKERVDGWKLKQDKGAIPMTNGTSIAPSEGRGVGDIDASTDYNMEDALLNDETRQPLSRKVPLPSSRINPYRMVIVLRLVVLSIFLHYRITNPVRNAYPLWLLSVICEIWFALSWILDQFPKWFPINRETYLDRLALRYDREGEPSQLAAVDIFVSTVDPMKEPPLVTANTVLSILAVDYPVDKVSCYVSDDGAAMLTFDALAETSEFARKWVPFVKKYNIEPRAPEWYFSQKIDYLKDKVHPSFVKDRRAMKREYEEFKVRINGLVAKAQKVPEEGWIMQDGTPWPGNNTRDHPGMIQVFLGHSGGLDTEGNELPRLVYVSREKRPGFQHHKKAGAMNALVRVSAVLTNGQYMLNLDCDHYINNSKALREAMCFLMDPNLGRSVCYVQFPQRFDGIDRNDRYANRNTVFFDINLRGLDGIQGPVYVGTGCVFNRTALYGYEPPIKQKKKGSFLSSLCGGRKKASKSKKKSSDKKKSNKHVDSAVPVFNLEDIEEGVEGAGFDDEKSLLMSQMSLEKRFGQSAAFVASTLMEYGGVPQSATPESLLKEAIHVISCGYEDKTEWGTEIGWIYGSVTEDILTGFKMHARGWRSIYCMPKRPAFKGSAPINLSDRLNQVLRWALGSVEILFSRHCPIWYGYGGRLKFLERFAYINTTIYPLTSIPLLIYCVLPAICLLTGKFIIPEISNFASIWFISLFISIFATGILEMRWSGVGIDEWWRNEQFWVIGGISAHLFAVFQGLLKVLAGIDTNFTVTSKASDEDGDFAELYMFKWTTLLIPPTTILIINLVGVVAGISYAINSGYQSWGPLFGKLFFAFWVIVHLYPFLKGLMGRQNRTPTIVVVWAILLASIFSLLWVRIDPFTTRVTGPDTQTCGINC

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0P0X3V1A0A0P0X3V1_ORYSJOs07g0208500294

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP003748
EMBL· GenBank· DDBJ
BAD30175.1
EMBL· GenBank· DDBJ
Genomic DNA
AP003837
EMBL· GenBank· DDBJ
BAC57282.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008213
EMBL· GenBank· DDBJ
BAF21076.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014963
EMBL· GenBank· DDBJ
BAT00571.1
EMBL· GenBank· DDBJ
Genomic DNA
CM000144
EMBL· GenBank· DDBJ
EAZ39084.1
EMBL· GenBank· DDBJ
Genomic DNA
AK072356
EMBL· GenBank· DDBJ
BAG92935.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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